Reina Jordi, Gutiérrez Olivia, Ruiz de Gopegui Enrique, Padilla Emma
Servicio de Microbiología Clínica, Hospital Universitario Son Dureta, Plama de Mallorca, Spain.
Enferm Infecc Microbiol Clin. 2005 Oct;23(8):482-4. doi: 10.1157/13078827.
In recent years studies from various parts of the world have reported a significant increase in the number of genital infections caused by HSV-1, especially among women.
We report a study of genital infections caused by HSV-1 in our geographic area from 1995 to 2003. Genital samples were inoculated in the Vero cell line and cultures were stained by monoclonal antibodies against HSV-1 and HSV-2.
During the study period, 263 samples were positive for herpesviruses: 146 for HSV-1 (55.5%) and 117 for HSV-2 (44.5%). The 20 HSV-1 isolated in the genital tract represented 7.6% of all the herpesviruses isolated in this study. Of the 146 HSV-1 isolated, 20 (13.7%) were obtained in genital samples, 15 (75%) in women and 5 (25%) in men (p < 0.005). Four men (80%) were homosexual. No patient, male or female, was infected with the HIV and none worked as prostitutes.
The percentage of HSV-1 genital infections increased in the last year of the study (33%), especially among women from the general population. The herpesvirus isolated in these samples should be characterized, since, in general, HSV-1 does not usually develop latency or recurrent infections in this anatomical area.
近年来，世界各地的研究报告称，由单纯疱疹病毒1型（HSV - 1）引起的生殖器感染数量显著增加，尤其是在女性中。
我们报告了一项关于1995年至2003年我们所在地理区域内由HSV - 1引起的生殖器感染的研究。将生殖器样本接种到非洲绿猴肾细胞系中，并用抗HSV - 1和HSV - 2的单克隆抗体对培养物进行染色。
在研究期间，263份样本的疱疹病毒检测呈阳性：146份为HSV - 1（55.5%），117份为HSV - 2（44.5%）。在生殖道分离出的20株HSV - 1占本研究中分离出的所有疱疹病毒的7.6%。在分离出的146株HSV - 1中，20株（13.7%）来自生殖器样本，其中15株（75%）来自女性，5株（25%）来自男性（p < 0.005）。4名男性（80%）为同性恋者。没有患者（无论男性还是女性）感染艾滋病毒，也没有从事性工作者。
在研究的最后一年，HSV - 1生殖器感染的比例有所增加（33%），尤其是在普通人群中的女性中。应对这些样本中分离出的疱疹病毒进行特征鉴定，因为一般来说，HSV - 1通常不会在这个解剖区域形成潜伏感染或复发性感染。
