Faerk K K
Open Care Unit, Edsbyn, Sweden.
J Intern Med. 1992 Jun;231(6):621-2. doi: 10.1111/j.1365-2796.1992.tb01249.x.
The case of a married couple who simultaneously developed polymyalgia rheumatica is presented. Both patients responded to steroid treatment, and when the steroid dose was gradually reduced both patients relapsed. The aetiology and pathogenesis of polymyalgia rheumatica remain unclear; familial aggregation indicates the involvement of genetic factors, whereas conjugal aggregation indicates infectious/environmental agents. In previous reports of polymyalgia rheumatica in married couples, the onset of symptoms in the two patients has usually been separated by a long chronological interval. It is concluded that the present report of simultaneous development of polymyalgia rheumatica in a married couple lends further support to an environmental or contagious aetiology.
本文报告了一对已婚夫妇同时患上风湿性多肌痛的病例。两位患者对类固醇治疗均有反应,当类固醇剂量逐渐减小时,两位患者均复发。风湿性多肌痛的病因和发病机制仍不清楚;家族聚集表明遗传因素的参与,而配偶聚集则表明感染/环境因素的作用。在以往关于已婚夫妇患风湿性多肌痛的报告中,两位患者症状的出现通常在时间上间隔较长。结论是,本报告中一对已婚夫妇同时患上风湿性多肌痛,进一步支持了环境或传染性病因的观点。