Diukman R, Golbus M S
Department of Obstetrics, Gynecology and Reproductive Sciences, University of California Medical Center, San Francisco 94143-0720.
J Reprod Med. 1992 Jun;37(6):515-20.
In utero stem cell transplantation offers the potential for treating a number of genetic disorders. The combination of fetal immunotolerance and fetal marrow space makes the fetus an excellent transplant recipient. Experiments on the mouse, sheep and rhesus monkey have indicated that in utero transplantation is feasible. Human trials are currently beginning.
子宫内干细胞移植为治疗多种遗传性疾病提供了可能性。胎儿的免疫耐受性和胎儿骨髓空间相结合,使胎儿成为理想的移植受体。在小鼠、绵羊和恒河猴身上进行的实验表明,子宫内移植是可行的。目前人类试验正在开始。