Koyama S, Koike N, Saito T, Todoroki T, Mori N, Fukutomi H
Department of Internal Medicine, University of Tsukuba.
Jpn J Clin Oncol. 1992 Apr;22(2):136-41.
A case of early gastric plasmacytoma in a 51-year-old woman is reported. The demonstration of monotypic IgM-kappa immunoglobulin in biopsy specimens by an immunoperoxidase technique contributed to the histological diagnosis. The patient had non-ulcerative lesions (of approximately 15 x 16 cm) of a superficially spreading type of gastric plasmacytoma. Extensive histological analysis of the resected stomach showed the IgM-kappa monoclonal proliferation of plasmacytic tumor cells to infiltrate merely into the lamina propria of the gastric mucosa and not to extend deeply into the submucosa, proper muscle and serosa of the stomach.
报告了一例51岁女性的早期胃浆细胞瘤。通过免疫过氧化物酶技术在活检标本中检测到单型IgM-κ免疫球蛋白有助于组织学诊断。患者患有浅表扩散型胃浆细胞瘤的非溃疡性病变（约15×16厘米）。对切除胃的广泛组织学分析显示，浆细胞肿瘤细胞的IgM-κ单克隆增殖仅浸润至胃黏膜固有层，未深入浸润至胃黏膜下层、固有肌层和浆膜层。
