[腺样体肥大与分泌性中耳炎的关系]
[The relationship between adenoids hypertrophy and secretory otitis media].
作者信息
Yin Guiru, Yue Zhuoli, Hu Jiangong, Zhao Xiaoming
机构信息
Department of Otolaryngology, the Affiliated Hospital of Chengde Medical College, Chengde, 067000, China.
出版信息
Lin Chuang Er Bi Yan Hou Ke Za Zhi. 2005 Jul;19(13):588-9.
OBJECTIVE
To investigate the relationship between immune status of adenoids and secretory otitis media (SOM).
METHOD
All the 76 cases of SOM were divided into 2 groups: recurrent group (46 cases) and control group (30 cases whose occurrence was less than 3 times). The manifestation of CD45RO, CD20, PCNA and BCL-2 in adenoids was detected with ultrasensitive (TM)S-P immunohistology.
RESULT
The expression of CD44Ro, CD20, PCNA and BCL-2 in recurrent group was significantly higher than that in control group (P < 0.05 or P < 0.01).
CONCLUSION
In adenoid tissues of recurrent SOM patients, the activities of lymphocytes and cells in hypertrophic status increase, the adenoids enlarge and local immunity enhances. Therefore, adenoidectomy for SOM patients should be carried out as early as possible.
目的
探讨腺样体免疫状态与分泌性中耳炎（SOM）之间的关系。
方法
将76例分泌性中耳炎患者分为两组：复发组（46例）和对照组（发作次数少于3次的30例）。采用超敏（TM）S-P免疫组织化学法检测腺样体中CD45RO、CD20、PCNA和BCL-2的表达情况。
结果
复发组中CD44Ro、CD20、PCNA和BCL-2的表达明显高于对照组（P<0.05或P<0.01）。
结论
复发性分泌性中耳炎患者的腺样体组织中，淋巴细胞及肥大状态细胞的活性增加，腺样体增大，局部免疫力增强。因此，分泌性中耳炎患者应尽早行腺样体切除术。
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