Bradbeer T M, Fleming P M, Charlton P, Crichton J S
St James' Hospital, Portsmouth, UK.
Drug Alcohol Rev. 1998 Sep;17(3):299-304. doi: 10.1080/09595239800187131.
A survey was undertaken of senior medical specialists in drug dependence in England and Wales, enquiring about their attitudes and practices concerning the prescription of amphetamines to dependent users. Of the 149 who replied, 60% saw a role for amphetamine prescribing, with 46% currently doing so. Of those who did not prescribe, 32% would like to have done so. Respondents often did not know if general practitioners in their area were prescribing amphetamines. Many could not estimate the percentage of injecting amphetamine users in their area. There was a wide range in the dosage of amphetamine prescribed with a mean maximum of 66 mg. There was agreement about entry criteria for prescribing programmes and also on ways of monitoring those receiving amphetamine. Our results indicate that amphetamine prescribing is widespread in England and Wales although there is little scientific evidence for its efficacy. We have developed some guidelines for good practice, drawing on our own and others' experience.
针对英格兰和威尔士的资深药物依赖医学专家开展了一项调查,询问他们对于向药物依赖使用者开具苯丙胺处方的态度和做法。在149位回复者中,60%认为开具苯丙胺有其作用,其中46%目前正在这样做。在那些不开具处方的人中,32%表示愿意开具。受访者常常不知道所在地区的全科医生是否在开具苯丙胺处方。许多人无法估计所在地区注射苯丙胺使用者的比例。所开具的苯丙胺剂量范围很广,平均最大剂量为66毫克。对于处方项目的准入标准以及监测苯丙胺接受者的方式存在共识。我们的结果表明,尽管几乎没有科学证据证明其疗效,但在英格兰和威尔士开具苯丙胺处方的情况很普遍。我们借鉴自身及他人的经验,制定了一些良好做法指南。