Wooley Jennifer, Pomerantz Richard
St. Joseph Mercy Hospital, Clinical Nutrition/Pharmacy, Ann Arbor, MI 48106, USA.
Nutr Clin Pract. 2005 Jun;20(3):348-53. doi: 10.1177/0115426505020003348.
Proper enteral access to deliver specialized nutrition support in critically injured patients can be difficult, time consuming, and costly. We designed a protocol with interdisciplinary input to facilitate early enteral access in our trauma patients. Our primary objective was to determine if the protocol improved our ability to obtain small-bowel access in patients within 48 hours of their admission to the surgical intensive care unit (SICU). Secondary objectives were to examine the efficacy of the protocol by evaluating parenteral nutrition (PN) use, adequacy of enteral caloric delivery, and clinical outcomes including pneumonia and sepsis rates, SICU length of stay (LOS), hospital LOS, and mortality before and after its implementation.
The medical records of 51 trauma patients admitted to the SICU, who met inclusion criteria, were reviewed retrospectively and divided into 2 groups. Patients in group 1 were admitted before protocol implementation (1997-1998, n = 17). Patients in group 2 were admitted after protocol implementation (1998-2000, n = 34).
Small-bowel access was achieved earlier in group 2 compared with group 1 [2.2 +/- 2 days vs 5.4 +/- 8 days, respectively (p = .04)]. PN was used less frequently in group 2 at 41.2% (14/34) as opposed to 64.7% (11/17) in group 1 (p = .05). There was a reduction in the number of days to reach caloric goal from 4.9 days in group 1 to 3.9 days in group 2 (n.s.). Clinical outcomes were similar in both groups.
The use of a protocol was effective in the achievement of prompt small bowel access. The number of days to reach caloric goal decreased after protocol implementation, but not to a statistically significant degree. However, we were able to detect a significant reduction in the use of PN.
在重症创伤患者中,建立合适的肠内通路以提供特殊营养支持可能困难、耗时且成本高昂。我们设计了一项由多学科共同参与的方案,以促进创伤患者早期建立肠内通路。我们的主要目标是确定该方案是否提高了我们在患者入住外科重症监护病房(SICU)48小时内获得小肠通路的能力。次要目标是通过评估肠外营养(PN)的使用、肠内热量供应的充足性以及包括肺炎和败血症发生率、SICU住院时间(LOS)、医院住院时间和实施该方案前后的死亡率等临床结局,来检验该方案的有效性。
对51例入住SICU且符合纳入标准的创伤患者的病历进行回顾性分析,并分为两组。第1组患者在方案实施前入院(1997 - 1998年,n = 17)。第2组患者在方案实施后入院(1998 - 2000年,n = 34)。
与第1组相比,第2组更早实现小肠通路[分别为2.2±2天和5.4±8天(p = 0.04)]。第2组PN的使用频率较低,为41.2%(14/34),而第1组为64.7%(11/17)(p = 0.05)。达到热量目标的天数从第1组的4.9天减少到第2组的3.9天(无统计学差异)。两组的临床结局相似。
使用该方案有效地实现了快速的小肠通路建立。方案实施后达到热量目标的天数有所减少,但未达到统计学显著程度。然而,我们能够检测到PN使用的显著减少。