丹麦的土拉菌病：通过实时聚合酶链反应鉴定土拉热弗朗西斯菌全北区亚种菌株并采用多位点可变数目串联重复序列分析进行高分辨率分型
Tularemia in Denmark: identification of a Francisella tularensis subsp. holarctica strain by real-time PCR and high-resolution typing by multiple-locus variable-number tandem repeat analysis.
作者信息
Byström Mona, Böcher Sidsel, Magnusson Anna, Prag Jørgen, Johansson Anders
机构信息
Department of NBC-Analysis, Swedish Defence Research Agency, SE-901 82 Umeå, Sweden.
出版信息
J Clin Microbiol. 2005 Oct;43(10):5355-8. doi: 10.1128/JCM.43.10.5355-5358.2005.
Abstract
We report ulceroglandular tularemia affecting an 8-year-old boy and the first recovery of Francisella tularensis in Denmark. A novel real-time PCR assay was used to identify the strain as F. tularensis subsp. holarctica (type B). Multiple-locus variable-number tandem repeat analysis demonstrated a close genetic relationship to strains from Norway.
摘要
我们报告了一例发生在一名8岁男孩身上的溃疡性腺型兔热病，以及丹麦首次分离出土拉弗朗西斯菌。采用一种新型实时聚合酶链反应检测法将该菌株鉴定为土拉弗朗西斯菌全北区亚种（B型）。多位点可变数目串联重复序列分析表明，该菌株与来自挪威的菌株具有密切的亲缘关系。
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Tularemia in Denmark: identification of a Francisella tularensis subsp. holarctica strain by real-time PCR and high-resolution typing by multiple-locus variable-number tandem repeat analysis.丹麦的土拉菌病：通过实时聚合酶链反应鉴定土拉热弗朗西斯菌全北区亚种菌株并采用多位点可变数目串联重复序列分析进行高分辨率分型
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