Sharma N C, Goyal C R, Qaqish J G, Cugini M A, Thompson M C, Warren P R
BioSci Research Canada Ltd., 6245 Mississauga Road, Mississauga, Ontario L5N 1A4, Canada.
J Dent. 2005 Jun;33 Suppl 1:11-5.
To compare the safety and plaque removal efficacy of two oscillating/rotating/pulsating toothbrushes (Oral-B ProfessionalCare 7000 [PC 7000] and Oral-B 3D Excel [3DE]) and a high-frequency toothbrush (Sonicare Advance, Philips Oral Healthcare; SA) in a single-use, examiner-blind, three period crossover study.
After refraining from all oral hygiene procedures for 23-25 hours, subjects received an oral tissue examination and those with pre-brushing whole mouth mean plaque scores > or = 0.6 based on the Rustogi et al. Modified Navy Plaque Index were randomly assigned to treatment sequence. After brushing with the assigned toothbrush and a commercially available dentifrice for 2 minutes, oral tissues were then re-examined and post-brushing plaque scores recorded. Following a brief washout period between two additional visits, the above procedures were repeated with the two alternate toothbrushes. One examiner, blinded to the treatment sequence, performed all clinical measurements.
A total of 79 subjects (28 males and 51 females) were enrolled and completed the study. Each toothbrush was found to be safe and significantly reduced plaque levels after a single brushing. The PC 7000 and 3DE were equally more effective in plaque removal than the SA, at all tooth areas, reducing plaque by 59.0%, 59.7% and 51.8%, respectively on whole mouth surfaces, and by 67.5%, 67.8% and 59.4%, respectively on approximal surfaces.
The action of the oscillating/rotating/pulsating toothbrushes (Oral-B ProfessionalCare 7000 and Oral-B 3D Excel) was more effective in plaque removal than the high-frequency toothbrush (Sonicare Advance).
在一项一次性使用、检查者盲法的三阶段交叉研究中，比较两种振荡/旋转/脉冲牙刷（欧乐B专业护理7000 [PC 7000]和欧乐B 3D卓越 [3DE]）与一种高频牙刷（飞利浦口腔护理声波震动牙刷进阶版；SA）的安全性和牙菌斑清除效果。
在停止所有口腔卫生程序23 - 25小时后，对受试者进行口腔组织检查，根据Rustogi等人改良的海军牙菌斑指数，刷牙前全口平均牙菌斑评分≥0.6的受试者被随机分配到治疗序列。使用指定牙刷和市售牙膏刷牙2分钟后，再次检查口腔组织并记录刷牙后的牙菌斑评分。在另外两次就诊之间有一个短暂的洗脱期，之后用另外两种交替的牙刷重复上述程序。一名对治疗序列不知情的检查者进行所有临床测量。
共招募了79名受试者（28名男性和51名女性）并完成了研究。发现每支牙刷都是安全的，并且单次刷牙后能显著降低牙菌斑水平。在所有牙齿区域，PC 7000和3DE在清除牙菌斑方面比SA更有效，全口表面牙菌斑减少率分别为59.0%、59.7%和51.8%，邻面分别为67.5%、67.8%和59.4%。
振荡/旋转/脉冲牙刷（欧乐B专业护理7000和欧乐B 3D卓越）在清除牙菌斑方面比高频牙刷（飞利浦口腔护理声波震动牙刷进阶版）更有效。
