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阿片类药物在癌症疼痛中的作用。

The role of opioids in cancer pain.

作者信息

Quigley Columba

机构信息

Cancer Centre, Hammersmith Hospital, London W12 0HZ.

出版信息

BMJ. 2005 Oct 8;331(7520):825-9. doi: 10.1136/bmj.331.7520.825.

DOI:10.1136/bmj.331.7520.825
PMID:16210282
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1246085/
Abstract

Columba Quigley, as a specialist in palliative medicine, works in a hospital based support team. She also works with a community based palliative care team and in a hospice, where patients are admitted for terminal care, respite, and control of symptoms. Pain occurs often in patients with cancer, particularly those with advanced disease. In addition, pain is one of the most feared symptoms in people with a diagnosis of cancer. Using analgesics (particularly opioids) appropriately effectively controls cancer pain in most patients

摘要

科伦巴·奎格利作为一名姑息医学专家,在医院的支持团队中工作。她还与社区姑息治疗团队合作,并在一家临终关怀医院工作,在那里患者因晚期护理、缓解症状和控制症状而入院。疼痛在癌症患者中经常出现,尤其是那些患有晚期疾病的患者。此外,疼痛是癌症患者最害怕的症状之一。适当使用镇痛药(尤其是阿片类药物)能有效控制大多数患者的癌症疼痛。

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本文引用的文献

1
Transdermal buprenorphine in the treatment of chronic pain: results of a phase III, multicenter, randomized, double-blind, placebo-controlled study.透皮丁丙诺啡治疗慢性疼痛:一项III期、多中心、随机、双盲、安慰剂对照研究的结果
Clin Ther. 2004 Nov;26(11):1808-20. doi: 10.1016/j.clinthera.2004.11.008.
2
Opioid switching to improve pain relief and drug tolerability.阿片类药物转换以改善疼痛缓解和药物耐受性。
Cochrane Database Syst Rev. 2004(3):CD004847. doi: 10.1002/14651858.CD004847.
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Methadone for cancer pain.用于癌症疼痛的美沙酮。
Cochrane Database Syst Rev. 2004(2):CD003971. doi: 10.1002/14651858.CD003971.pub2.
4
Transdermal fentanyl: informed prescribing is essential.透皮芬太尼:明智的处方开具至关重要。
Eur J Pain. 2003;7(5):481-3. doi: 10.1016/S1090-3801(02)00148-9.
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A systematic review of hydromorphone in acute and chronic pain.氢吗啡酮用于急慢性疼痛的系统评价。
J Pain Symptom Manage. 2003 Feb;25(2):169-78. doi: 10.1016/s0885-3924(02)00643-7.
6
Opioids versus antidepressants in postherpetic neuralgia: a randomized, placebo-controlled trial.阿片类药物与抗抑郁药治疗带状疱疹后神经痛的随机安慰剂对照试验
Neurology. 2002 Oct 8;59(7):1015-21. doi: 10.1212/wnl.59.7.1015.
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A randomised controlled study on the use of anti-inflammatory drugs in patients with cancer pain on morphine therapy: effects on dose-escalation and a pharmacoeconomic analysis.一项关于抗炎药物用于接受吗啡治疗的癌症疼痛患者的随机对照研究:对剂量递增的影响及药物经济学分析。
Eur J Cancer. 2002 Jul;38(10):1358-63. doi: 10.1016/s0959-8049(02)00102-8.
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Transdermal fentanyl for the management of cancer pain: a survey of 1005 patients.透皮芬太尼用于癌症疼痛的管理:对1005例患者的调查。
Palliat Med. 2001 Jul;15(4):309-21. doi: 10.1191/026921601678320296.
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J Pain Symptom Manage. 2001 Jun;21(6):448-9. doi: 10.1016/s0885-3924(01)00289-5.