Takeuchi Toshifumi, Mukawa Takashi, Shinmori Hideyuki
Graduate School of Science and Technology, Kobe University, 1-1 Rokkodai-cho, Kobe 657-8501, Japan.
Chem Rec. 2005;5(5):263-75. doi: 10.1002/tcr.20052.
Molecular imprinting is a template polymerization technique that can easily provide synthetic polymers capable of molecular recognition for given target molecules. In addition to their highly specific recognition ability, we are attempting to introduce signaling functions to molecularly imprinted polymers, enabling them to respond according to specific binding events. Some of our work regarding such signaling molecularly imprinted polymers is presented here, including molecularly imprinted polymers that induce spectral shifts of target compounds because of binding. Such compounds include hydrogen-bonding-based fluorescent imprinted polymers and metalloporphyrin-based signaling molecularly imprinted polymers.
分子印迹是一种模板聚合技术，它能够轻松地制备出对特定目标分子具有分子识别能力的合成聚合物。除了具有高度特异性的识别能力外，我们还试图将信号功能引入分子印迹聚合物，使其能够根据特定的结合事件做出响应。本文介绍了我们在这种信号分子印迹聚合物方面的一些工作，包括由于结合而导致目标化合物光谱发生位移的分子印迹聚合物。这类化合物包括基于氢键的荧光印迹聚合物和基于金属卟啉的信号分子印迹聚合物。
