Mathee Angela, Röllin Halina, von Schirnding Yasmin, Levin Jonathan, Naik Ina
South African Medical Research Council, P.O. Box 87373, Houghton 2041, South Africa.
Environ Res. 2006 Mar;100(3):319-22. doi: 10.1016/j.envres.2005.08.001. Epub 2005 Oct 6.
Epidemiological studies have indicated that in the 1980s and early 1990s (a period in which petrol lead concentrations in South Africa ranged from 0.836 to 0.4 g/L), large proportions of urban South African children were at risk of excessive exposure to environmental lead. In 1991, when the maximum permissible petrol lead concentration in the country equaled 0.4 g/L, a study determined that the mean blood lead level among children attending inner city schools in the Cape Peninsula equaled 16 microg/dL, with well over 90% of children having blood lead levels equaling or exceeding the internationally accepted guideline level of 10 microg/dL. Socio economic status, housing conditions, and proximity of children's schools and homes to heavily trafficked roads were among the factors significantly associated with blood lead concentrations. In 1996, unleaded petrol was introduced in South Africa. A study undertaken in 2002 (at the same schools as in 1991), when unleaded petrol constituted around 30% of the market share of petrol in the country, has shown significant reductions in the mean blood lead concentration among Cape Peninsula inner city children and in the proportion of children with elevated blood lead levels. The mean blood lead level for the total sample (n = 429) of children whose mean age equaled 7 years (range: 5-11 years) was 6.4 microg/dL (range: 1.0-24.5 microg/dL) and 10% of children had blood lead levels equalling or exceeding 10 microg/dL. The mean blood lead levels among children attending schools in an inner city and in a less heavily trafficked periurban suburb were 6.9 and 4.8 microg/dL, respectively.
流行病学研究表明,在20世纪80年代和90年代初(南非汽油铅浓度在0.836至0.4克/升之间的时期),很大比例的南非城市儿童面临环境铅暴露过量的风险。1991年,该国汽油铅的最大允许浓度为0.4克/升,一项研究确定,开普敦半岛市中心学校儿童的平均血铅水平为16微克/分升,超过90%的儿童血铅水平等于或超过国际公认的指导水平10微克/分升。社会经济地位、住房条件以及儿童学校和家庭与交通繁忙道路的距离是与血铅浓度显著相关的因素。1996年,南非开始使用无铅汽油。2002年(与1991年为同一批学校)进行的一项研究表明,在该国无铅汽油占汽油市场份额约30%时,开普敦半岛市中心儿童的平均血铅浓度以及血铅水平升高的儿童比例都有显著下降。平均年龄为7岁(范围:5至11岁)的儿童总样本(n = 429)的平均血铅水平为6.4微克/分升(范围:1.0至24.5微克/分升),10%的儿童血铅水平等于或超过10微克/分升。在市中心学校上学的儿童和交通不太繁忙的城郊郊区学校上学的儿童的平均血铅水平分别为6.9微克/分升和4.8微克/分升。