Institute for Health and Social Policy, McGill University, Montreal, QC, Canada.
Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, 1110 Pine Avenue West, Montreal, QC, H3A 1A3, Canada.
BMC Med. 2020 Feb 24;18(1):39. doi: 10.1186/s12916-020-1499-y.
As low- and middle-income countries urbanize and industrialize, they must also cope with pollution emitted from diverse sources.
Strong and consistent evidence associates exposure to air pollution and lead with increased risk of cardiovascular disease occurrence and death. Further, increasing evidence, mostly from high-income countries, indicates that exposure to noise and to both high and low temperatures may also increase cardiovascular risk. There is considerably less research on the cardiovascular impacts of environmental conditions in low- and middle-income countries (LMICs), where the levels of pollution are often higher and the types and sources of pollution markedly different from those in higher-income settings. However, as such evidence gathers, actions to reduce exposures to pollution in low- and middle-income countries are warranted, not least because such exposures are very high. Cities, where pollution, populations, and other cardiovascular risk factors are most concentrated, may be best suited to reduce the cardiovascular burden in LMICs by applying environmental standards and policies to mitigate pollution and by implementing interventions that target the most vulnerable. The physical environment of cities can be improved though municipal processes, including infrastructure development, energy and transportation planning, and public health actions. Local regulations can incentivize or inhibit the polluting behaviors of industries and individuals. Environmental monitoring can be combined with public health warning systems and publicly available exposure maps to inform residents of environmental hazards and encourage the adoption of pollution-avoiding behaviors. Targeted individual or neighborhood interventions that identify and treat high-risk populations (e.g., lead mitigation, portable air cleaners, and preventative medications) can also be leveraged in the very near term. Research will play a key role in evaluating whether these approaches achieve their intended benefits, and whether these benefits reach the most vulnerable.
Cities in LMICs can play a defining role in global health and cardiovascular disease prevention in the next several decades, as they are well poised to develop innovative, multisectoral approaches to pollution mitigation, while also protecting the most vulnerable.
随着中低收入国家的城市化和工业化,它们还必须应对来自各种来源的污染。
强有力且一致的证据表明,接触空气污染和铅会增加心血管疾病发生和死亡的风险。此外,越来越多的证据(主要来自高收入国家)表明,接触噪声以及高温和低温也可能增加心血管风险。关于中低收入国家(LMICs)环境条件对心血管的影响的研究要少得多,这些国家的污染水平通常更高,污染的类型和来源与高收入国家明显不同。然而,随着此类证据的积累,有必要采取行动减少中低收入国家的污染暴露,尤其是因为这些暴露水平非常高。城市是污染、人口和其他心血管危险因素最集中的地方,通过应用环境标准和政策来减轻污染,并实施针对最脆弱人群的干预措施,可能最适合减轻 LMICs 的心血管负担。通过城市进程,包括基础设施发展、能源和交通规划以及公共卫生行动,可以改善城市的物理环境。地方法规可以激励或抑制工业和个人的污染行为。可以将环境监测与公共卫生预警系统和公开可用的暴露图相结合,告知居民环境危害,并鼓励采取避免污染的行为。还可以在近期内利用针对高危人群的针对性个体或社区干预措施(例如,铅缓解、便携式空气净化器和预防性药物)。研究将在评估这些方法是否实现其预期效益以及这些效益是否惠及最弱势群体方面发挥关键作用。
在未来几十年,中低收入国家的城市可以在全球健康和心血管疾病预防方面发挥决定性作用,因为它们非常适合制定创新的、多部门的污染缓解方法,同时保护最弱势群体。