Rainone Francine
Albert Einstein College of Medicine of Yeshiva University, Bronx, New York.
Am Fam Physician. 2005 Oct 1;72(7):1285-8.
Milk thistle has been used as a cytoprotectant for the treatment of liver disease, for the treatment and prevention of cancer, and as a supportive treatment of Amanita phalloides poisoning. Clinical studies are largely heterogeneous and contradictory. Aside from mild gastrointestinal distress and allergic reactions, side effects are rare, and serious toxicity rarely has been reported. In an oral form standardized to contain 70 to 80 percent silymarin, milk thistle appears to be safe for up to 41 months of use. Significant drug reactions have not been reported. Clinical studies in oncology and infectious disease that are under way will help determine the efficacy and effectiveness of milk thistle.
水飞蓟已被用作细胞保护剂，用于治疗肝病、治疗和预防癌症，以及作为毒蝇伞中毒的支持性治疗。临床研究在很大程度上存在异质性且相互矛盾。除了轻微的胃肠道不适和过敏反应外，副作用很少见，严重毒性的报道也很少。以标准化形式口服，含有70%至80%水飞蓟素，水飞蓟连续使用长达41个月似乎是安全的。尚未有重大药物反应的报道。正在进行的肿瘤学和传染病方面的临床研究将有助于确定水飞蓟的疗效和有效性。
