Kim Jae Ho, Lee Dae Hyoung, Lee Seung Hwan, Choi Shin Yang, Lee Jong Soo
Department of Genetic Engineering, Paichai University, Daejeon 302-735, Korea.
J Biosci Bioeng. 2004;97(1):24-8. doi: 10.1016/S1389-1723(04)70160-7.
The goal of this study was to develop a high value Korean traditional rice wine possessing the pharmaceutical functionality of Ganoderma lucidum. The effects of the fruiting body of G. lucidum on the alcohol fermentation of Korean traditional rice wine, yakju, were investigated. Optimal fermentation conditions for the preparation of G. lucidum-yakju consisted of the koji added at 15% and a fermentation period of 15 d at 25 degrees C. The effects of the amount of G. lucidum added on the acceptability and functionality of G. lucidum-yakju were investigated. G. lucidum GL-1 yakju brewed by adding 0.1% G. lucidum into the mash showed the best acceptability and its angiotensin I-converting enzyme (ACE) inhibitory activity and SOD-like activity were 63% and 42%, respectively, both of which are higher than those of yakju. The high ACE inhibitory activity of G. lucidum GL-1 yakju was found to result from ganoderic acid K in G. lucidum on the basis of physical and spectral data. However, the fibrinolytic activity and antioxidant activity of G. lucidum GL-1 yakju were very low, while tyrosinase inhibitory activity was not determined. From these results, G. lucidum GL-1 yakju may become a new functional Korean traditional rice wine with antihypertensive properties.
本研究的目的是开发一种具有灵芝药用功能的高价值韩国传统米酒。研究了灵芝子实体对韩国传统米酒——浊酒酒精发酵的影响。制备灵芝浊酒的最佳发酵条件为:曲添加量为15%,在25℃下发酵15天。研究了灵芝添加量对灵芝浊酒可接受性和功能的影响。通过在醪液中添加0.1%灵芝酿造的灵芝GL-1浊酒表现出最佳的可接受性,其血管紧张素I转换酶(ACE)抑制活性和超氧化物歧化酶样活性分别为63%和42%,均高于浊酒。根据物理和光谱数据,发现灵芝GL-1浊酒的高ACE抑制活性是由灵芝中的灵芝酸K引起的。然而,灵芝GL-1浊酒的纤溶活性和抗氧化活性非常低,而酪氨酸酶抑制活性未测定。根据这些结果,灵芝GL-1浊酒可能成为一种具有抗高血压特性的新型功能性韩国传统米酒。