von Baum Heike, Marre Reinhard
Department of Medical Microbiology and Hygiene, University of Ulm, Robert-Koch-Str. 8, D-89081 Ulm, Germany.
Int J Med Microbiol. 2005 Oct;295(6-7):503-11. doi: 10.1016/j.ijmm.2005.07.002.
Widespread antibiotic resistance has been recognized in Escherichia coli isolates from human, animal and environmental sources. Although prevalence rates for resistant E. coli strains are significantly distinct for various populations and environments, the impact of resistance to antimicrobial drugs is ubiquitous. This article provides information about the epidemiology, mechanisms and molecular principles of resistance, shows consequences for the antiinfective treatment of selected infections and describes measures to control the spread of antibiotic-resistant E. coli.
在从人类、动物和环境来源分离出的大肠杆菌中，广泛存在抗生素耐药性。尽管耐药大肠杆菌菌株在不同人群和环境中的流行率存在显著差异，但抗菌药物耐药性的影响却是普遍存在的。本文提供了有关耐药性的流行病学、机制和分子原理的信息，展示了对某些感染进行抗感染治疗的后果，并描述了控制抗生素耐药性大肠杆菌传播的措施。
