Russell C O, Bright N, Buthpitiya G, Alexander L, Walton C, Whelan G
Monash University Department of Gastrointestinal Surgery, Monash Medical Centre, Melbourne, Vic., Australia.
Gut. 1992 Jun;33(6):727-32. doi: 10.1136/gut.33.6.727.
A fixed volume capsule incorporating a force transducer and a side hole for manometric measurements was constructed and calibrated. Simultaneous measurements of the propulsive (aboral) force and the manometric pressure (intraluminal pressure) were made at 5, 10, and 15 cm above the lower oesophageal sphincter and in response to dry and wet (5, 10, and 15 ml) swallows. The propulsive force and manometric pressure waves had a simultaneous onset and were of similar duration. Peak values of propulsive force for wet swallows increased significantly as measurements were made progressively more distally within the oesophagus and were greatest in the distal oesophagus. The association between manometric pressure and propulsive force is not strong (r = 0.61) suggesting that intraluminal pressure is a poor predictor of propulsive force and hence an unreliable measure of oesophageal 'function'.
制作并校准了一个装有力传感器和用于测压测量的侧孔的固定容积胶囊。在食管下括约肌上方5厘米、10厘米和15厘米处，以及对干吞咽和湿吞咽（5毫升、10毫升和15毫升）的反应中，同时测量推进力（向口力）和测压压力（管腔内压力）。推进力和测压压力波同时开始，持续时间相似。随着在食管内测量位置逐渐向远端推进，湿吞咽时推进力的峰值显著增加，在食管远端最大。测压压力与推进力之间的关联不强（r = 0.61），这表明管腔内压力对推进力的预测能力较差，因此是食管“功能”的不可靠测量指标。
