Ostberg Per, Fernaeus Sven-Erik, Hellström Ke, Bogdanović Nenad, Wahlund Lars-Olof
Section for Clinical Geriatrics, Neurotec Department, Karolinska Institutet, Stockholm, Sweden.
Brain Lang. 2005 Nov;95(2):273-9. doi: 10.1016/j.bandl.2005.01.010.
We assessed verb fluency vs. noun and letter-based fluency in 199 subjects referred for cognitive complaints including Subjective Cognitive Impairment, Mild Cognitive Impairment, and Alzheimer's disease. ANCOVAs and factor analyses identified verb, noun, and letter-based fluency as distinct tasks. Verb fluency performance in Mild Cognitive Impairment differed significantly from Subjective Cognitive Impairment and Alzheimer's disease. Reduced verb fluency thus appears to be a linguistic marker for incipient dementia. One possibility is that the verb fluency deficit in Mild Cognitive Impairment results from degenerative processes known to occur in the parahippocampal region.
我们对199名因认知问题前来就诊的受试者进行了动词流畅性与名词及字母流畅性的评估，这些受试者包括主观认知障碍、轻度认知障碍和阿尔茨海默病患者。协方差分析和因子分析确定动词、名词及字母流畅性为不同的任务。轻度认知障碍患者的动词流畅性表现与主观认知障碍和阿尔茨海默病患者有显著差异。因此，动词流畅性降低似乎是早期痴呆的一个语言标志物。一种可能性是，轻度认知障碍患者的动词流畅性缺陷是由海马旁区域已知的退行性过程导致的。
