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经瞳孔温热疗法治疗的一名中国患者的局限性脉络膜血管瘤:病例报告

Circumscribed choroidal hemangioma in a Chinese patient treated using transpupillary thermotherapy: a case report.

作者信息

Wang Jia-Kang, Lai Pei-Ching, Yang Chung-May, Chen Chao-Hsun, Chang Shu-Wen

机构信息

Department of Ophthalmology, Far Eastern Memorial Hospital, National Taiwan University Hospital, Taipei, Taiwan.

出版信息

Kaohsiung J Med Sci. 2005 Sep;21(9):433-7. doi: 10.1016/S1607-551X(09)70147-0.

Abstract

We describe the first case of a Chinese patient with circumscribed choroidal hemangioma (CCH) effectively managed using transpupillary thermotherapy (TTT). A 57-year-old man had an elevated orange-red subretinal mass with a base of 5 x 5 mm superior to the optic disc, along with serous macular detachment in the left eye. Ultrasonography depicted a mass 3 mm thick with acoustic solidity and high internal reflectivity. Fluorescein angiography showed an area of hyperfluorescence in the prearterial phase and tumor staining in the late phase, consistent with a diagnosis of CCH. Therefore, TTT (spot size, 3 mm; exposure, 1 min) was performed with a diode laser, delivered through a slit-lamp biomicroscope. The laser power was first set at 300 mW and then increased in 50-mW increments, until test shots in the mid-peripheral retina outside the lesion produced a slightly grayish appearance in the irradiated area. The tumor was covered with four overlapping laser spots and subjected to an average beam power of 400 mW. Best-corrected visual acuity increased from 20/50 before treatment, to 20/20 3 months following one session of TTT. The lesion became atrophic and the subretinal fluid disappeared. Our experience shows that TTT can be an even more effective treatment strategy for CCH in Asians than in Caucasians. In Chinese patients, the power level of the diode laser should be lower than that used in Caucasians.

摘要

我们描述了首例使用经瞳孔温热疗法(TTT)有效治疗的中国局限性脉络膜血管瘤(CCH)患者。一名57岁男性左眼视盘上方有一个5×5mm大小的橘红色视网膜下隆起肿物,并伴有浆液性黄斑脱离。超声检查显示肿物厚3mm,呈声学实性且内部反射率高。荧光素血管造影显示动脉前期有高荧光区,晚期有肿瘤染色,符合CCH的诊断。因此,使用二极管激光通过裂隙灯生物显微镜进行TTT(光斑大小3mm;照射时间1分钟)。激光功率首先设定为300mW,然后以50mW的增量增加,直到在病变外的视网膜中周部进行测试照射时,照射区域出现轻微灰白色外观。肿瘤用四个重叠的激光光斑覆盖,平均光束功率为400mW。最佳矫正视力从治疗前的20/50提高到TTT治疗一次后3个月的20/20。病变萎缩,视网膜下液消失。我们的经验表明,对于亚洲人,TTT治疗CCH可能比高加索人更有效。在中国患者中,二极管激光的功率水平应低于高加索人使用的功率水平。

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本文引用的文献

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Transpupillary thermotherapy (TTT) in circumscribed choroidal hemangioma.局限性脉络膜血管瘤的经瞳孔温热疗法(TTT)
Graefes Arch Clin Exp Ophthalmol. 2002 Jan;240(1):7-11. doi: 10.1007/s004170100350. Epub 2001 Nov 22.
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Transpupillary thermotherapy for circumscribed choroidal hemangiomas: first choice in therapy.
Eur J Ophthalmol. 2001 Jul-Sep;11(3):316-8. doi: 10.1177/112067210101100318.
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Transpupillary thermotherapy for circumscribed choroidal hemangiomas.
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