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使用液晶空间光调制器的三维自适应光学超高分辨率光学相干断层扫描

Three-dimensional adaptive optics ultrahigh-resolution optical coherence tomography using a liquid crystal spatial light modulator.

作者信息

Fernández Enrique J, Povazay Boris, Hermann Boris, Unterhuber Angelika, Sattmann Harald, Prieto Pedro M, Leitgeb Rainer, Ahnelt Peter, Artal Pablo, Drexler Wolfgang

机构信息

Center for Biomedical Engineering and Physics, Vienna University of Medicine, Austria.

出版信息

Vision Res. 2005 Dec;45(28):3432-44. doi: 10.1016/j.visres.2005.08.028. Epub 2005 Oct 24.

Abstract

A liquid crystal programmable phase modulator (PPM) is used as correcting device in an adaptive optics system for three-dimensional ultrahigh-resolution optical coherence tomography (UHR OCT). The feasibility of the PPM to correct high order aberrations even when using polychromatic light is studied, showing potential for future clinical use. Volumetric UHR OCT of the living retina, obtained with up 25,000A-scans/s and high resolution enables visualization of retinal features that might correspond to groups of terminal bars of photoreceptors at the external limiting membrane.

摘要

一种液晶可编程相位调制器(PPM)被用作三维超高分辨率光学相干断层扫描(UHR OCT)自适应光学系统中的校正装置。研究了PPM即使在使用多色光时校正高阶像差的可行性,显示出其在未来临床应用中的潜力。通过高达25000次A扫描/秒的速度和高分辨率获得的活体视网膜容积UHR OCT能够可视化可能与外部限制膜处光感受器终末棒组相对应的视网膜特征。

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