从一种鲁氏海绵属海洋海绵中分离得到的四种新型抗菌倍半萜。

Four new antibacterial sesterterpenes from a marine sponge of the genus Luffariella.

作者信息

König G M, Wright A D, Sticher O

机构信息

Department of Pharmacy, Swiss Federal Institute of Technology (ETH), Zurich.

出版信息

J Nat Prod. 1992 Feb;55(2):174-8. doi: 10.1021/np50080a004.

DOI:10.1021/np50080a004

PMID:1624940

Abstract

The structures of four new sesterterpenoid compounds 1-4 isolated from a marine sponge of the genus Luffariella, collected from The Great Barrier Reef, Australia, have been determined by analysis of their 1H-nmr, 13C-nmr, ir, uv, and eims spectral data. The new metabolites 1-4 were found to co-occur with the compounds manoalide, secomanoalide, Z-neomanolaide [5], and E-neomanoalide.

摘要

从澳大利亚大堡礁采集的一种卢氏海绵属海洋海绵中分离出的四种新的倍半萜化合物1-4的结构，已通过对其1H-核磁共振、13C-核磁共振、红外、紫外和电子轰击质谱光谱数据的分析得以确定。发现新的代谢产物1-4与化合物软海绵素、去甲软海绵素、Z-新软海绵素[5]和E-新软海绵素共同存在。