Taylor Andrew M, Dymarkowski Steven, Verbeken Eric K, Bogaert Jan
Cardiothoracic Unit, Great Ormond Street Hospital for Children, Great Ormond Street, London, WC1N 3JH, UK.
Eur Radiol. 2006 Mar;16(3):569-74. doi: 10.1007/s00330-005-0025-0. Epub 2005 Oct 25.
To examine the value of late-enhancement cardiac magnetic resonance imaging (MRI) for detection of pericardial inflammation.
Late-enhancement cardiac MRI was performed in 16 patients with clinical suspicion of pericardial disease. Pericardial effusion, pericardial thickening and pericardial enhancement were assessed. MRI findings were compared with those of definitive pericardial histology (n=14) or microbiology (n=2). A control group of 12 patients with no clinical evidence of pericardial disease were also imaged with the same MRI protocol.
Sensitivity and specificity for late-enhancement MRI detection of pericardial inflammation was of 100%. There was MRI late enhancement of the pericardial layers in all five patients with histological/microbiological evidence of inflammatory pericarditis. MRI demonstrated no pericardial thickening and no MRI late enhancement with or without a pericardial effusion in any of the five patients with histological evidence of a normal pericardium. MRI detected pericardial thickening in the absence of both pericardial effusion and late enhancement in all six patients with histological evidence of chronic fibrosing pericarditis. The 12 control subjects showed no evidence of pericardial MRI late enhancement.
These findings demonstrate that MRI late enhancement can be used to visualize pericardial inflammation in patients with clinical suspicion of pericardial disease.
探讨延迟强化心脏磁共振成像（MRI）在检测心包炎症中的价值。
对16例临床怀疑心包疾病的患者进行延迟强化心脏MRI检查。评估心包积液、心包增厚和心包强化情况。将MRI检查结果与心包组织学确诊结果（n = 14）或微生物学确诊结果（n = 2）进行比较。还对12例无临床心包疾病证据的患者组成的对照组采用相同的MRI检查方案进行成像。
延迟强化MRI检测心包炎症的敏感性和特异性均为100%。在所有5例经组织学/微生物学证实为炎性心包炎的患者中，心包各层均出现MRI延迟强化。在5例经组织学证实心包正常的患者中，无论有无心包积液，MRI均未显示心包增厚及MRI延迟强化。在所有6例经组织学证实为慢性纤维性心包炎的患者中，MRI在无心包积液和延迟强化的情况下检测到心包增厚。12例对照受试者未显示心包MRI延迟强化的证据。
这些结果表明，MRI延迟强化可用于可视化临床怀疑心包疾病患者的心包炎症。
