Bane Catherine, Hughes Carmel M, McElnay James C
Programme Manager, Research and Development Office, Belfast, Northern Ireland, UK.
Patient Educ Couns. 2006 Feb;60(2):187-93. doi: 10.1016/j.pec.2005.01.003. Epub 2005 Oct 25.
This study sought to determine the influence of depression and psychosocial factors on medication adherence in cardiovascular disease.
A questionnaire including measures of depression, beliefs about medicines, health locus of control and adherence to medication (self-report) was completed by 122 outpatients attending a cardiac clinic.
Analysis revealed that 14.8% of participants were non-adherent with their cardiovascular medication and 41.7% had scores indicative of depressive symptoms as determined by the Center for Epidemiological Studies Depression Scale (CES-D). Higher scores on this scale and strong concern scores on the Beliefs about Medicines Questionnaire about the potential adverse effects of using medication as prescribed were found to be associated with self-reported non-adherence.
These findings imply that the relationship between depressive symptoms in cardiovascular patients, together with certain psychosocial factors, could have negative consequences for adherence to medication.
Given that there is emerging evidence to suggest an association between depression and medication non-adherence, healthcare professionals should consider this when dealing with cardiovascular patients.
本研究旨在确定抑郁症和社会心理因素对心血管疾病患者药物依从性的影响。
一份包含抑郁症测量、用药信念、健康控制点和药物依从性(自我报告)的问卷由122名前往心脏科门诊的患者完成。
分析显示,14.8%的参与者未坚持服用心血管药物,41.7%的参与者根据流行病学研究中心抑郁量表(CES-D)的得分表明有抑郁症状。该量表得分较高以及用药信念问卷中对按处方用药潜在不良反应的强烈担忧得分较高,均与自我报告的不依从性相关。
这些发现表明,心血管疾病患者的抑郁症状与某些社会心理因素之间的关系可能对药物依从性产生负面影响。
鉴于越来越多的证据表明抑郁症与药物不依从性之间存在关联,医疗保健专业人员在处理心血管疾病患者时应考虑到这一点。