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[葡萄球菌毒素对微循环系统的影响]

[Effect of staphylococcal toxin on the microcirculatory system].

作者信息

Brill' G E, Sergeev I P, Glazkova E I, Morokhovets N V

出版信息

Patol Fiziol Eksp Ter. 1992 Jan-Feb(1):21-3.

PMID:1625923
Abstract

Study of microcirculation in the mesentery of narcotized rats showed that the staphylococcal toxin causes increased migration of leukocytes, aggregation of formed elements, and disturbance of the blood flow in the small venules and arterioles. The toxin stimulates rhythmic contractile activity of the lymphatic microvessels and induces their constriction and even complete obliteration. The lymphoconstrictive effect of the toxin is weakened by verapamil and completely removed by dimethyl sulfoxide.

摘要

对麻醉大鼠肠系膜微循环的研究表明,葡萄球菌毒素会导致白细胞迁移增加、血液有形成分聚集,以及小静脉和小动脉内血流紊乱。该毒素刺激淋巴微血管的节律性收缩活动,并导致其收缩甚至完全闭塞。维拉帕米可减弱该毒素的淋巴管收缩作用,而二甲基亚砜则可完全消除这种作用。

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1
[Effect of staphylococcal toxin on the microcirculatory system].[葡萄球菌毒素对微循环系统的影响]
Patol Fiziol Eksp Ter. 1992 Jan-Feb(1):21-3.
2
[The effect of dimethyl sulfoxide on the changes in the lymph microcirculation induced by staphylococcal toxin].[二甲基亚砜对葡萄球菌毒素所致淋巴微循环变化的影响]
Eksp Klin Farmakol. 1998 Jul-Aug;61(4):54-6.
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[Effect of bacterial toxins on microcirculation (experimental research)].[细菌毒素对微循环的影响(实验研究)]
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[Effect of endothelin on rat mesenteric microvessels].[内皮素对大鼠肠系膜微血管的作用]
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Microvasc Res. 2006 Nov;72(3):108-12. doi: 10.1016/j.mvr.2006.04.007. Epub 2006 Oct 9.
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Clin Hemorheol Microcirc. 2008;40(2):119-31.
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Effects of carpronium chloride on the microvascular blood flow in rat mesentery using intravital videomicroscopy.用活体视频显微镜观察氯化卡普隆铵对大鼠肠系膜微血管血流的影响。
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[Influence of burned skin toxin on the state of hemodynamics in rats].[烧伤皮肤毒素对大鼠血流动力学状态的影响]
Biull Eksp Biol Med. 1976 Mar;81(3):275-6.
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[Participation of Ca-dependent systems in thrombocyte aggregation induced by the action of staphylococcal toxin and ADP].[钙依赖系统在葡萄球菌毒素和二磷酸腺苷作用诱导的血小板聚集中的参与情况]
Nauchnye Doki Vyss Shkoly Biol Nauki. 1985(7):23-6.

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Advances in small animal mesentery models for in vivo flow cytometry, dynamic microscopy, and drug screening.用于体内流式细胞术、动态显微镜检查和药物筛选的小动物肠系膜模型的进展。
World J Gastroenterol. 2007 Jan 14;13(2):192-218. doi: 10.3748/wjg.v13.i2.192.