Sazama K, Kuramoto I K, Holland P V, Couroucé A M, Gallo D, Hanson C V
Sacramento Medical Foundation Center for Blood Research, California.
Transfusion. 1992 Jun;32(5):398-401. doi: 10.1046/j.1537-2995.1992.32592327710.x.
Twelve serum samples from French blood donors that were uniformly reactive in tests for antibody to human immunodeficiency virus type 2 (anti-HIV-2) also were reactive in 92 to 100 percent of tests with three anti-HIV type 1 (anti-HIV-1) enzyme-linked immunoassays currently in widespread use for donor screening in the United States. Supplemental tests for anti-HIV-1 on these anti-HIV-2-reactive samples differed in their responses. All samples reacted in a licensed anti-HIV-1 Western blot, but there was an atypical band near the p41 position, which could be a clue to the fact that this result was a cross-reaction with anti-HIV-2. A recombinant immunoblot gave an indeterminate result for anti-HIV-1 in all 12 samples. A local immunofluorescence assay for anti-HIV-1 reacted with 92 percent of the samples, but a commercial one detected only 58 percent.
来自法国献血者的12份血清样本在检测2型人类免疫缺陷病毒抗体（抗-HIV-2）时呈一致反应，在美国目前广泛用于献血者筛查的三种1型人类免疫缺陷病毒（抗-HIV-1）酶联免疫测定中，92%至100%的检测也呈反应性。对这些抗-HIV-2反应性样本进行的抗-HIV-1补充检测反应各不相同。所有样本在经许可的抗-HIV-1免疫印迹法中均呈反应性，但在p41位置附近有一条非典型条带，这可能暗示该结果是与抗-HIV-2的交叉反应。重组免疫印迹法对所有12份样本的抗-HIV-1检测结果均不确定。一种抗-HIV-1的局部免疫荧光测定法与92%的样本发生反应，但一种商业检测法仅检测到58%。
