Kohno T, Miki T, Kitashoji K
Department of Ophthalmology, Osaka City University Medical School, Japan.
Nippon Ganka Gakkai Zasshi. 1992 Jun;96(6):749-56.
Retinal opacity was experimentally induced by blunt trauma to the rabbit eye and the damage to the choroidal circulation was investigated immediately thereafter by using indocyanine green (ICG) videoangiography. Ten pigmented rabbit eyes were used. In the early phase, the defect of choroidal inflow (10 eyes), the twitch of the choroidal artery (2 eyes) and the reflux of the vortex vein (5 eyes) could be observed dynamically. The defect of choroidal inflow showed its peak around the point where the choroidal arteries branched off from ciliary arteries and disappeared within a few second to over ten seconds. The reflux from the vortex vein seemed to be important as collateral pathway. In the middle phase, several points of ICG leakage were observed around the apex of the delayed area of choroidal circulation (9 eyes). This ICG leakage was intra-choroidal and seemed to be caused by the breakdown of the great vessels at the outer layer of the choroid. This study indicates that ICG videoangiography could observe various choroidal circulatory disturbances following blunt trauma and may be useful in delineating the pathogenesis of retinal opacity.
通过对兔眼进行钝挫伤实验性诱导视网膜混浊，随后立即使用吲哚菁绿（ICG）血管造影术研究脉络膜循环的损伤情况。使用了10只色素沉着的兔眼。在早期阶段，可动态观察到脉络膜血流缺损（10只眼）、脉络膜动脉抽搐（2只眼）和涡静脉反流（5只眼）。脉络膜血流缺损在脉络膜动脉从睫状动脉分支处附近达到峰值，并在几秒到十几秒内消失。涡静脉反流似乎作为侧支循环途径很重要。在中期阶段，在脉络膜循环延迟区域的顶端周围观察到几个ICG渗漏点（9只眼）。这种ICG渗漏发生在脉络膜内，似乎是由脉络膜外层大血管破裂引起的。本研究表明，ICG血管造影术可以观察钝挫伤后各种脉络膜循环障碍，可能有助于阐明视网膜混浊的发病机制。
