Hay-McCutcheon Marcia J, Brown Carolyn J, Abbas Paul J
Department of Speech Pathology and Audiology, University of Iowa, Iowa City, Iowa 52242, USA.
J Acoust Soc Am. 2005 Oct;118(4):2444-57. doi: 10.1121/1.2035593.
The objective of this study was to determine the impact that auditory-nerve adaptation has on behavioral measures of temporal integration in Nucleus 24 cochlear implant recipients. It was expected that, because the auditory nerve serves as the input to central temporal integrator, a large degree of auditory-nerve adaptation would reduce the amount of temporal integration. Neural adaptation was measured by tracking amplitude changes of the electrically evoked compound action potential (ECAP) in response to 1000-pps biphasic pulse trains of varying durations. Temporal integration was measured at both suprathreshold and threshold levels by an adaptive procedure. Although varying degrees of neural adaptation and temporal integration were observed across individuals, results of this investigation revealed no correlation between the degree of neural adaptation and psychophysical measures of temporal integration.
本研究的目的是确定听觉神经适应对24型核人工耳蜗植入者时间整合行为测量的影响。预计由于听觉神经作为中枢时间整合器的输入，较大程度的听觉神经适应会减少时间整合量。通过跟踪不同持续时间的1000pps双相脉冲序列诱发的电诱发复合动作电位（ECAP）的幅度变化来测量神经适应。通过自适应程序在阈上和阈水平测量时间整合。虽然在个体间观察到不同程度的神经适应和时间整合，但本研究结果显示神经适应程度与时间整合的心理物理学测量之间没有相关性。
