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基底神经节:学习新技能并乐在其中。

The basal ganglia: learning new tricks and loving it.

作者信息

Graybiel Ann M

机构信息

Department of Brain and Cognitive Sciences and the McGovern Institute for Brain Research, Massachusetts Institute of Technology, 43 Vassar Street, 46-6133, Cambridge, MA, 02139 USA.

出版信息

Curr Opin Neurobiol. 2005 Dec;15(6):638-44. doi: 10.1016/j.conb.2005.10.006. Epub 2005 Nov 3.

Abstract

The field of basal ganglia research is exploding on every level - from discoveries at the molecular level to those based on human brain imaging. A remarkable series of new findings support the view that the basal ganglia are essential for some forms of learning-related plasticity. Other new findings are challenging some of the basic tenets of the field as it now stands. Combined with the new evidence on learning-related functions of the basal ganglia, these studies suggest that the basal ganglia are parts of a brain-wide set of adaptive neural systems promoting optimal motor and cognitive control.

摘要

基底神经节的研究领域正在各个层面蓬勃发展——从分子层面的发现到基于人类脑成像的发现。一系列引人注目的新发现支持了这样一种观点,即基底神经节对于某些形式的与学习相关的可塑性至关重要。其他新发现正在挑战该领域目前的一些基本信条。结合关于基底神经节与学习相关功能的新证据,这些研究表明基底神经节是促进最佳运动和认知控制的全脑适应性神经系统的一部分。

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