Jozsa R, Halberg F, Cornélissen G, Zeman M, Kazsaki J, Csernus V, Katinas G S, Wendt H W, Schwartzkopff O, Stebelova K, Dulkova K, Chibisov S M, Engebretson M, Pan W, Bubenik G A, Nagy G, Herold M, Hardeland R, Hüther G, Pöggeler B, Tarquini R, Perfetto F, Salti R, Olah A, Csokas N, Delmore P, Otsuka K, Bakken E E, Allen J, Amory-Mazaudin C
University Pécs, Pécs, Hungary.
Biomed Pharmacother. 2005 Oct;59 Suppl 1(Suppl 1):S24-30. doi: 10.1016/s0753-3322(05)80006-x.
A multi-center four-hourly sampling of many tissues for 7 days (00:00 on April 5-20:00 to April 11, 2004), on rats standardized for 1 month in two rooms on antiphasic lighting regimens happened to start on the day after the second extremum of a moderate double magnetic storm gauged by the planetary geomagnetic Kp index (which at each extremum reached 6.3 international [arbitrary] units) and by an equatorial index Dst falling to -112 and -81 nT, respectively, the latter on the first day of the sampling. Neuroendocrine chronomes (specifically circadian time structures) differed during magnetically affected and quiet days. The circadian melatonin rhythm had a lower MESOR and lower circadian amplitude and tended to advance in acrophase, while the MESOR and amplitude of the hypothalamic circadian melatonin rhythm were higher during the days with the storm. The circadian parameters of circulating corticosterone were more labile during the days including the storm than during the last three quiet days. Feedsidewards within the pineal-hypothalamic-adrenocortical network constitute a mechanism underlying physiological and probably also pathological associations of the brain and heart with magnetic storms. Investigators in many fields can gain from at least recording calendar dates in any publication so that freely available information on geomagnetic, solar and other physical environmental activity can be looked up. In planning studies and before starting, one may gain from consulting forecasts and the highly reliable nowcasts, respectively.
对大鼠在两个房间按照反相光照方案进行1个月的标准化处理后,于2004年4月5日00:00至4月11日20:00期间,对多种组织进行为期7天、每4小时一次的多中心采样。采样恰巧始于由行星地磁Kp指数测量的中等强度双磁暴的第二个极值(每次极值达到6.3国际[任意]单位)之后的一天,同时赤道指数Dst分别降至-112和-81 nT,后者发生在采样的第一天。在受磁影响的日子和安静的日子里,神经内分泌生物钟(特别是昼夜节律时间结构)有所不同。昼夜褪黑素节律的中值昼夜节律振幅较低,且相位峰值趋于提前,而在磁暴期间,下丘脑昼夜褪黑素节律的中值昼夜节律振幅较高。与最后三个安静日子相比,包括磁暴期间的日子里,循环皮质酮的昼夜节律参数更不稳定。松果体 - 下丘脑 - 肾上腺皮质网络内的反馈构成了大脑和心脏与磁暴生理及可能病理关联的潜在机制。许多领域的研究人员至少可以在任何出版物中记录日期,以便查阅关于地磁、太阳和其他物理环境活动的免费信息。在规划研究时和开始之前,分别参考预报和高度可靠的临近预报可能会有所帮助。