Schwenk W, Neudecker J, Raue W, Haase O, Müller J M
Department of General, Visceral, Vascular and Thoracic Surgery, Humboldt University, Charité, Campus Mitte, Berlin, Germany.
Int J Colorectal Dis. 2006 Sep;21(6):547-53. doi: 10.1007/s00384-005-0056-7. Epub 2005 Nov 9.
After rectal cancer surgery, postoperative general complications occur in 25-35% of all patients and postoperative hospital stay is 14-21 days. "Fast-track" rehabilitation has been shown to accelerate recovery, reduce general morbidity and decrease hospital stay after elective colonic surgery. Because the feasibility of "fast-track" rehabilitation in patients undergoing rectal cancer surgery has not been demonstrated yet, we demonstrate our initial results of "fast-track" rectal cancer surgery.
Seventy consecutive unselected patients undergoing rectal cancer resection by one surgeon underwent a perioperative "fast-track" rehabilitation. Demographic and operative data, pulmonary function, pain and fatigue, local and general complications and mortality were assessed prospectively.
Thirty-six female and 34 male patients aged 65 (34-77) years underwent open (n=31) or laparoscopic (n=39) anterior resection with partial mesorectal excision (PME 27), anterior resection with total mesorectal excision and protective loop ileostomy (TME 29) or abdominoperineal excision with colostomy (APR 14). Overall, pulmonary function returned to >80% of preoperative value on day 2 (1-4) and the first bowel movement occurred on day 1 (0-3) after surgery. The incidence of local and general complications was 27 and 18%, respectively. Postoperative hospital stay was 8 (3-50) days overall, but shorter after PME [5 (3-47)] than TME [10 (5-42)] or APR [9 (5-50)] (p<0.01).
"Fast-track" rehabilitation was feasible in patients undergoing rectal cancer resection. Local morbidity was not increased, while general morbidity and postoperative hospital stay compared favourably to other series with "traditional" perioperative care.
直肠癌手术后,25% - 35%的患者会出现术后全身并发症,术后住院时间为14 - 21天。“快速康复”已被证明可加速择期结肠手术后的恢复,降低全身发病率并缩短住院时间。由于“快速康复”在直肠癌手术患者中的可行性尚未得到证实,我们展示了“快速康复”直肠癌手术的初步结果。
由一名外科医生连续为70例未经选择的直肠癌切除术患者进行围手术期“快速康复”。前瞻性评估人口统计学和手术数据、肺功能、疼痛与疲劳、局部和全身并发症以及死亡率。
36例女性和34例男性患者,年龄65(34 - 77)岁,接受了开放手术(n = 31)或腹腔镜手术(n = 39),术式包括局部系膜直肠切除的前切除术(PME 27例)、全直肠系膜切除及保护性回肠造口的前切除术(TME 29例)或经腹会阴联合切除及结肠造口术(APR 14例)。总体而言,术后第2天(1 - 4天)肺功能恢复至术前值的>80%,术后第1天(0 - 3天)首次排便。局部和全身并发症的发生率分别为27%和18%。术后总体住院时间为8(3 - 50)天,但PME术后住院时间[5(3 - 47)天]短于TME术后[10(5 - 42)天]或APR术后[9(5 - 50)天](p<0.01)。
“快速康复”在直肠癌切除患者中是可行的。局部发病率未增加,而全身发病率和术后住院时间与其他采用“传统”围手术期护理的系列研究相比更具优势。