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[眼线笔中紫胶和1,3 - 丁二醇引起的变应性接触性湿疹]

[Allergic contact eczema from shellac and 1,3-butylene glycol in an eyeliner].

作者信息

Magerl Alexander, Pirker Claudia, Frosch Peter J

机构信息

Hautklinik, Klinikum Dortmund.

出版信息

J Dtsch Dermatol Ges. 2003 Apr;1(4):300-2.

Abstract

BACKGROUND

The diagnostic approach to eyelid eczema is often a great problem in daily practice.

PATIENT AND METHOD

A 16-year old girl developed recurrent severe pruritic edema of the eyelids, followed by redness and scaling. Various cosmetics particularly an eyeliner were considered as possible causes. Patch testing was performed with the standard series, some supplemental series and all ingredients of the eyeliner.

RESULTS

The eyeliner produced a papular reaction after 2 days of open application, confirming a high degree of contact sensitization. The patient reacted with a 3+ reaction to the ingredients shellac (20% in ethanol) and 1,3-butylene glycol (2% in water). All remaining materials failed to produce a reaction.

CONCLUSIONS

Careful allergologic investigations are necessary in cases of edema and/or eczema of the eyelids; the cosmetics used by the patients are of utmost importance. The causative allergen may not be present in the usual patch test series and can only be identified by testing all ingredients. Shellac is now widely used in cosmetics and is increasingly identified as a contact allergen in eye make up.

摘要

背景

在日常实践中,眼睑湿疹的诊断方法常常是个大问题。

患者与方法

一名16岁女孩出现反复发作的严重眼睑瘙痒性水肿,随后出现发红和脱屑。各种化妆品尤其是眼线笔被认为是可能的病因。用标准系列、一些补充系列以及眼线笔的所有成分进行了斑贴试验。

结果

眼线笔在开放涂抹2天后产生丘疹反应,证实有高度接触致敏性。患者对紫胶(乙醇中20%)和1,3 - 丁二醇(水中2%)成分产生3 +反应。其余所有材料均未产生反应。

结论

对于眼睑水肿和/或湿疹病例,进行仔细的变应性学检查很有必要;患者使用的化妆品至关重要。致病变应原可能不在常用的斑贴试验系列中,只能通过检测所有成分来识别。紫胶目前在化妆品中广泛使用,并且越来越多地被确认为眼部化妆品中的接触变应原。

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