Bach Kevin K, Belafsky Peter C, Wasylik Kathleen, Postma Gregory N, Koufman Jamie A
Department of Otolaryngology/Head and Neck Surgery, Naval Medical Center San Diego, San Diego, Calif, USA.
Arch Otolaryngol Head Neck Surg. 2005 Nov;131(11):961-4. doi: 10.1001/archotol.131.11.961.
To evaluate a symptom-focused vocal impairment instrument for the evaluation of patients with voice disorders.
Prospective, nonrandomized study of patients with voice disorders undergoing treatment with validation of a new symptom index, the Glottal Function Index (GFI).
Voice disorders clinic at an academic tertiary care hospital.
Consecutive patients undergoing therapy for glottal insufficiency, adductor spasmodic dysphonia, nodules, and granuloma (40 patients in each group) and 40 control patients.
The Pearson correlation coefficient was used to evaluate GFI reproducibility and to compare it with the Voice Handicap Index (VHI). The paired-samples t test was used to compare pretherapy and posttherapy GFI values.
Correlation of GFI with VHI; comparison of the GFI in normals, and in pretherapy and posttherapy GFI and VHI scores.
The mean +/- SD normative GFI score was 0.87 +/- 1.32. The correlation coefficient for GFI between independent pretherapy measurements was 0.56 (P<.001). The correlation coefficient between total GFI and total VHI scores was 0.61 (P<.001). The mean posttherapy GFI scores improved among all groups as follows: glottal insufficiency: presenting GFI score, 12.7 +/- 4.1; posttherapy GFI score, 6.8 +/- 5.4; nodules: presenting GFI score, 12.9 +/- 4.2; posttherapy GFI score, 8.9 +/- 4.6; adductor spasmodic dysphonia: presenting GFI score, 13.2 +/- 4.1; posttherapy GFI score, 8.9 +/- 4.9; and granuloma: presenting GFI score, 7.8 +/- 4.6; posttherapy GFI score, 3.8 +/- 2.1. Relative to controls, the GFI score at presentation was significantly elevated and demonstrated significant reduction following treatment across each of these entities (P<.05).
The GFI is a reliable, reproducible, 4-item, self-administered symptom index with excellent criterion-based and construct validity. Its advantages over existing indexes include brevity and ease of administration. The GFI is a useful adjunct in the evaluation and treatment of patients with glottal dysfunction.
评估一种以症状为重点的嗓音障碍评估工具，用于嗓音疾病患者的评估。
对接受治疗的嗓音疾病患者进行前瞻性、非随机研究，验证一种新的症状指数——声门功能指数（GFI）。
一所学术性三级护理医院的嗓音疾病诊所。
连续纳入因声门闭合不全、内收肌痉挛性发音障碍、声带小结和肉芽肿接受治疗的患者（每组40例）以及40例对照患者。
采用Pearson相关系数评估GFI的可重复性，并将其与嗓音障碍指数（VHI）进行比较。采用配对样本t检验比较治疗前和治疗后的GFI值。
GFI与VHI的相关性；正常人群、治疗前和治疗后GFI及VHI评分的比较。
GFI的平均±标准差正常评分是0.87±1.32。独立治疗前测量的GFI之间的相关系数为0.56（P<0.001）。总GFI与总VHI评分之间的相关系数为0.61（P<0.001）。所有组治疗后的GFI平均评分改善情况如下：声门闭合不全：治疗前GFI评分，12.7±4.1；治疗后GFI评分，6.8±5.4；声带小结：治疗前GFI评分，12.9±4.2；治疗后GFI评分，8.9±4.6；内收肌痉挛性发音障碍：治疗前GFI评分，13.2±4.1；治疗后GFI评分，8.9±4.9；肉芽肿：治疗前GFI评分，7.8±4.6；治疗后GFI评分，3.8±2.1。相对于对照组，各疾病治疗前的GFI评分显著升高，治疗后均显著降低（P<0.05）。
GFI是一种可靠、可重复的4项自我管理症状指数，具有出色的基于标准和结构效度。其相对于现有指数的优势包括简短和易于实施。GFI是声门功能障碍患者评估和治疗中的有用辅助工具。
