Kwong Y M, Cho P
Department of Optometry & Radiography, The Hong Kong Polytechnic University, Hung Hom, Kowloon, Hong Kong.
Cont Lens Anterior Eye. 1998;21(1):11-4. doi: 10.1016/s1367-0484(98)80018-0.
Two cotton thread tests (a self-prepared cotton thread test (SP-CTT) and the Phenol Red Thread (PRT) test) were performed on 46 dry eye and 37 normal Hong Kong (HK)-Chinese, all subjects being diagnosed by ophthalmologists in a private clinic. The mean SP-CTT value for the dry eye subjects (mean +/- SD: 6.2 +/- 4.2 mm/15s) was significantly lower than that of the normal subjects (8.3 +/- 4.3 mm/15s). However, no significant difference in the mean PRT value was found between the two groups (dry eye subjects: 10.7 +/- 4.5 mm/15s; normal subjects; 11.4 +/- 4.5 mm/15s). The specificity and sensitivity of the SP-CTT were 78.4% and 45.7 when a cut-off value of < or = 4 mm was used, and 56.8% and 65.2% when the cut-off value was changed to < or = 6.5 mm. Our results showed that the specificities and sensitivities of both tests were poor when applied to these dry eye patients.
对46名干眼症患者和37名正常香港华人进行了两项棉线试验（一项自制棉线试验（SP - CTT）和酚红棉线（PRT）试验），所有受试者均在一家私人诊所由眼科医生诊断。干眼症受试者的SP - CTT平均值（平均值±标准差：6.2±4.2毫米/15秒）显著低于正常受试者（8.3±4.3毫米/15秒）。然而，两组之间的PRT平均值没有显著差异（干眼症受试者：10.7±4.5毫米/15秒；正常受试者：11.4±4.5毫米/15秒）。当使用≤4毫米的临界值时，SP - CTT的特异性和敏感性分别为78.4%和45.7，当临界值改为≤6.5毫米时，特异性和敏感性分别为56.8%和65.2%。我们的结果表明，将这两项试验应用于这些干眼症患者时，其特异性和敏感性都很差。
