Richman R M, Steinbeck K S, Caterson I D
Department of Endocrinology, Royal Prince Alfred Hospital, Camperdown, NSW.
Med J Aust. 1992 Jun 1;156(11):768-70. doi: 10.5694/j.1326-5377.1992.tb121558.x.
To determine the efficacy of two dietary therapies in both the short term (hospitalisation) and the longer term treatment of severe obesity.
A descriptive study of two patient groups with obesity defined by a body mass index of greater than 30 kg/m2.
A multidisciplinary weight control program in a tertiary care hospital.
All admissions to hospital of patients on the weight control program for initiation of weight loss during a period of 48 months.
A standard kilojoule reduction regimen or the use of complete, followed by partial, long term meal substitution with a very low energy liquid diet (VLED), coupled with an exercise and a behavioural modification program.
Weight loss during and after hospitalisation was measured in both dietary regimen groups.
Both diets induced weight loss in hospital. Men prescribed VLED lost significantly more weight, 8.3 +/- 0.8 kg (mean +/- SEM) than women prescribed this diet (5.5 +/- 0.5 kg) or standard kilojoule restriction (5.1 +/- 0.8 kg).
VLED and standard kilojoule restriction are both effective for the treatment of severe obesity, particularly in a controlled environment (hospitalisation). In the longer term, VLED is an effective method of maintaining weight loss. Lack of continuing weight loss may reflect the patients who were initially placed on this regimen--small eaters with a presumed high metabolic efficiency.
确定两种饮食疗法在短期(住院期间)和长期治疗重度肥胖症中的疗效。
对两组体重指数大于30kg/m²的肥胖患者进行描述性研究。
一家三级护理医院的多学科体重控制项目。
在48个月期间,体重控制项目中所有因开始减肥而入院的患者。
采用标准的减少千焦摄入量方案,或使用完全代餐,随后部分代餐,采用极低能量流食(VLED)进行长期代餐,并结合运动和行为改变计划。
测量两个饮食方案组患者住院期间及出院后的体重减轻情况。
两种饮食方案均能使患者在住院期间体重减轻。采用VLED的男性患者体重减轻显著更多,为8.3±0.8kg(均值±标准误),高于采用该饮食方案的女性患者(5.5±0.5kg)或采用标准千焦限制饮食的患者(5.1±0.8kg)。
VLED和标准千焦限制饮食对重度肥胖症的治疗均有效,尤其是在可控环境(住院期间)。从长期来看,VLED是维持体重减轻的有效方法。体重不再持续减轻可能反映出最初采用该方案的患者——食量小且推测代谢效率高。