Schornack Muriel
Department of Ophthalmology, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Cont Lens Anterior Eye. 2003 Sep;26(3):153-9. doi: 10.1016/S1367-0484(03)00026-2.
Although contact lens-induced corneal warpage is most frequently associated with PMMA lenses, approximately 27% of reported cases of corneal warpage have been attributed to hydrogel lens wear. The change in corneal contour may be the result of either mechanical deformation, chronic metabolic insult, or a combination of mechanical and metabolic challenges. Limited oxygen transmissibility through some hydrogel lenses may lead to chronic hypoxia and acidosis. These metabolic challenges can change corneal physiology sufficiently to cause clinically significant corneal warpage.
Three cases of hydrogel contact lens-induced corneal warpage are presented. In all three cases, cessation of lens wear led to restoration of the normal corneal contour and visual acuity. All patients were refit with more oxygen-permeable lenses, and have successfully resumed wearing contact lenses.
Certain individuals who wear hydrogel contact lenses can experience corneal warpage. Clinical signs of corneal warpage include changes in refractive error, decreased visual acuity with spectacle correction, and changes in corneal topography. Serial topography is useful to monitor the cornea to resolution of the condition. Contact lenses with higher oxygen transmissibility will frequently alleviate the relative hypoxia that may be associated with corneal warpage.
尽管角膜接触镜诱导的角膜变形最常与聚甲基丙烯酸甲酯(PMMA)镜片相关,但在报告的角膜变形病例中,约27%归因于水凝胶镜片的佩戴。角膜轮廓的改变可能是机械变形、慢性代谢损伤或机械与代谢挑战共同作用的结果。一些水凝胶镜片的透氧性有限可能导致慢性缺氧和酸中毒。这些代谢挑战可充分改变角膜生理,从而导致具有临床意义的角膜变形。
本文报告了3例水凝胶接触镜诱导的角膜变形病例。在所有3例病例中,停止佩戴镜片后角膜轮廓恢复正常,视力也得以恢复。所有患者均重新佩戴了透氧性更高的镜片,并成功恢复了隐形眼镜佩戴。
佩戴水凝胶接触镜的某些个体可能会出现角膜变形。角膜变形的临床体征包括屈光不正改变、戴眼镜矫正视力下降以及角膜地形图改变。连续的地形图检查有助于监测角膜直至病情缓解。透氧性更高的隐形眼镜通常可缓解可能与角膜变形相关的相对缺氧情况。