Alipour Fateme, Letafatnejad Mojgan, Beheshtnejad Amir Hooshang, Mohammadi Seyed-Farzad, Ghaffary Seyed Reza, Hassanpoor Narges, Yaseri Mehdi
Eye Research Center, Farabi Eye Hospital, Tehran University of Medical Sciences, Tehran, Iran.
Tehran University of Medical Sciences, Tehran, Iran.
J Ophthalmol. 2016;2016:5603763. doi: 10.1155/2016/5603763. Epub 2016 Sep 4.
Purpose. To evaluate the difference in biomechanical properties between contact lens induced corneal warpage and normal and keratoconic eyes. Method. Prospective observational case control study, where 94 eyes of 47 warpage suspicious and 46 eyes of 23 keratoconic patients were included. Warpage suspected cases were followed until a definite diagnosis was made (warpage, normal, or keratoconus). Results. 44 eyes of 22 patients had contact lens related corneal warpage. 46 eyes of 23 people were diagnosed as nonwarpage normal eyes. 46 eyes of 23 known keratoconus patients were included for comparison. The mean age of the participants was 23.8 ± 3.8 years, and 66.2% of the subjects were female. The demographic and refractive data were not different between warpage and normal groups but were different in the keratoconus group. The biomechanical properties (corneal hysteresis or CH and corneal resistance factor or CRF) were different with the highest value in the warpage group followed by normal and keratoconus groups. CRF was 10.08 ± 1.75, 9.23 ± 1.22, and 7.38 ± 2.14 and CH was 10.21 ± 1.57, 9.59 ± 1.21, and 8.69 ± 2.34 in the warpage, normal, and keratoconus groups, respectively. Conclusion. Corneal biomechanics may be different in people who develop contact lens induced warpage.
目的。评估隐形眼镜引起的角膜变形与正常眼和圆锥角膜眼之间生物力学特性的差异。方法。前瞻性观察性病例对照研究,纳入47例疑似角膜变形患者的94只眼和23例圆锥角膜患者的46只眼。对疑似角膜变形病例进行随访,直至做出明确诊断(角膜变形、正常或圆锥角膜)。结果。22例患者的44只眼患有与隐形眼镜相关的角膜变形。23人的46只眼被诊断为非变形正常眼。纳入23例已知圆锥角膜患者的46只眼进行比较。参与者的平均年龄为23.8±3.8岁,66.2%的受试者为女性。角膜变形组和正常组的人口统计学和屈光数据无差异,但圆锥角膜组不同。生物力学特性(角膜滞后或CH和角膜阻力因子或CRF)不同,角膜变形组的值最高,其次是正常组和圆锥角膜组。角膜变形组、正常组和圆锥角膜组的CRF分别为10.08±1.75、9.23±1.22和7.38±2.14,CH分别为10.21±1.57、9.59±1.21和8.69±2.34。结论。发生隐形眼镜引起的角膜变形的人群角膜生物力学可能不同。