Huang Pochi, Zwang-Weissman Jeremy, Weissman Barry A
Department of Organismic Biology, Ecology & Evolution, College of Letters and Science, University of California, Los Angeles, USA.
Cont Lens Anterior Eye. 2004 Mar;27(1):9-14. doi: 10.1016/j.clae.2003.09.005.
We studied oxygen supply to the contact lens covered cornea by means of a complex calculation method. We measured lens thicknesses, both centrally and at a 3mm peripheral location, of a range of optical powers of two different spherical silicone hydrogel contact lens designs (manufactured by Ciba Vision and Bausch & Lomb) and one "traditional" hydrogel. Using the measured values of lens thickness and the nominal oxygen permeabilities of these three plastics, we calculated the oxygen tension level in the tear layer posterior to the contact lens and anterior to the cornea and the oxygen flux through these contact lenses, under both open- and closed-eye conditions. We conclude that variable thicknesses of the silicone hydrogel contact lenses does not significantly affect the oxygen tension in the entrapped tear layer, given their high oxygen diffusion coefficients, under open-eye conditions, and probably only minimally under closed-eye conditions as well.
我们通过一种复杂的计算方法研究了覆盖在角膜上的隐形眼镜的氧气供应情况。我们测量了两种不同球面硅水凝胶隐形眼镜设计(由视康和博士伦生产)以及一种“传统”水凝胶的一系列屈光度镜片在中心和周边3mm位置的厚度。利用所测量的镜片厚度值以及这三种材料的标称透氧率,我们计算了在睁眼和闭眼条件下,隐形眼镜后方泪液层和角膜前方的氧分压水平以及通过这些隐形眼镜的氧通量。我们得出结论,在睁眼条件下,鉴于硅水凝胶隐形眼镜具有较高的氧扩散系数,其厚度变化对被困泪液层中的氧分压没有显著影响,在闭眼条件下可能影响也极小。