自由基清除剂：老年性聋的一种治疗方法。一项初步研究。
Radical scavengers: a remedy for presbyacusis. A pilot study.
作者信息
Takumida Masaya, Anniko Matti
机构信息
Department of Otolaryngology, Hiroshima University School of Medicine, Hiroshima, Japan.
出版信息
Acta Otolaryngol. 2005 Dec;125(12):1290-5. doi: 10.1080/00016480510037032.
CONCLUSION
The results of this study suggest that treatment with radical scavengers has the potential to become an effective new therapy for presbyacusis.
OBJECTIVE
To assess the efficacy of treatment with the radical scavengers rebamipide and vitamin C for presbyacusis.
MATERIAL AND METHODS
Rebamipide (300 mg/day) and vitamin C (600 mg/day) were taken orally for at least 8 weeks by 23 patients with presbyacusis.
RESULTS
Hearing levels after treatment were significantly improved at 125, 250, 500 and 8000 Hz but unchanged at 1000, 2000 and 4000 Hz.
结论
本研究结果表明，用自由基清除剂治疗有可能成为一种治疗老年性耳聋的有效新疗法。
目的
评估自由基清除剂瑞巴派特和维生素C治疗老年性耳聋的疗效。
材料与方法
23例老年性耳聋患者口服瑞巴派特（300毫克/天）和维生素C（600毫克/天）至少8周。
结果
治疗后的听力水平在125、250、500和8000赫兹时显著改善，但在1000、2000和4000赫兹时未改变。
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