Coats Mary, Morris John C
Memory and Aging Project, Washington University School of Medicine, St. Louis, MO 63108, USA.
J Geriatr Psychiatry Neurol. 2005 Dec;18(4):242-4. doi: 10.1177/0891988705281881.
The Washington University Adult Children Study is a longitudinal study to develop and validate biological markers, imaging features, and other indicators of preclinical Alzheimer's disease to aid in identifying individuals at high risk for developing symptomatic Alzheimer's disease. Two groups of participants between the ages of 45 and 74 are being enrolled in the Adult Children Study. Group 1 represents adult children who have at least 1 parent with Alzheimer's disease. Group 2 represents adult children whose parents have lived at least to age 70 without dementia. The Adult Children Study participants have been highly motivated to participate, and this study will require the investment of many years from the participants and the investigators before its most significant results will be known.
华盛顿大学成年子女研究是一项纵向研究，旨在开发和验证生物标志物、影像学特征以及临床前阿尔茨海默病的其他指标，以帮助识别有发展为症状性阿尔茨海默病高风险的个体。两组年龄在45岁至74岁之间的参与者正在被纳入成年子女研究。第一组代表至少有1名患阿尔茨海默病父母的成年子女。第二组代表其父母至少活到70岁且无痴呆症的成年子女。成年子女研究的参与者积极性很高，这项研究在取得最显著成果之前，将需要参与者和研究人员投入多年时间。
