Shubert P J, Diss E, Iams J D
Department of Obstetrics and Gynecology, Ohio State University College of Medicine, Columbus.
Obstet Gynecol Clin North Am. 1992 Jun;19(2):251-63.
Numerous factors have been indicted as playing a role in causing preterm premature rupture of membranes (PPROM). After discussing the development of the amnion and chorion, this article focuses primarily on the effects that infection, nutrition, smoking, and cervical incompetence have on the fetal membrane and the subsequent advent of PPROM. However, evidence continues to support a multifactorial etiology for this entity, with numerous factors acting in concert.
许多因素被认为在导致胎膜早破（PPROM）中起作用。在讨论羊膜和绒毛膜的发育之后，本文主要关注感染、营养、吸烟和宫颈机能不全对胎膜以及随后PPROM发生的影响。然而，证据仍支持该病症的多因素病因，众多因素共同起作用。
