人羊膜：在口腔及牙周领域的潜在应用
Human Amnion Membrane: Potential Applications in Oral and Periodontal Field.
作者信息
Mohan Ranjana, Bajaj Aashima, Gundappa Mohan
机构信息
Department of Periodontics, Teerthanker Mahaveer Dental College and Research Centre, Moradabad, Uttar Pradesh, India.
Department of Conservative Dentistry and Endodontics, Teerthanker Mahaveer Dental College and Research Centre, Moradabad, Uttar Pradesh, India.
出版信息
J Int Soc Prev Community Dent. 2017 Jan-Feb;7(1):15-21. doi: 10.4103/jispcd.JISPCD_359_16. Epub 2017 Feb 21.
Abstract
Human amniotic membrane (HAM) is derived from the fetal membranes which consist of the inner amniotic membrane made of single layer of amnion cells fixed to collagen-rich mesenchyme attached to chorion. HAM has low immunogenicity, anti-inflammatory properties and their cells can be isolated without the sacrifice of human embryos. Amniotic membrane has biological properties which are important for the experimental and clinical applications in managing patients of various medical specialties. Abundant, natural and wonderful biomembrane not only protects the foetus but also has various clinical applications in the field of dermatology, ophthalmology, ENT surgery, orthopedics and dental surgery. As it is discarded post-partum it may be useful for regenerative medicine and cell therapy to treat damaged or diseased tissues.
摘要
人羊膜（HAM）源自胎膜，胎膜由内层羊膜组成，内层羊膜由单层羊膜细胞构成，这些细胞附着于富含胶原蛋白的间充质上，而间充质又附着于绒毛膜。HAM具有低免疫原性、抗炎特性，并且可以分离其细胞而无需牺牲人类胚胎。羊膜具有生物学特性，这些特性对于各个医学专业治疗患者的实验和临床应用都很重要。这种丰富、天然且出色的生物膜不仅能保护胎儿，还在皮肤科、眼科、耳鼻喉科手术、骨科和牙科手术领域有多种临床应用。由于它在产后被丢弃，可能对再生医学和细胞治疗受损或患病组织有用。
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