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膈上憩室的病因及治疗

Cause and treatment of epiphrenic diverticula.

作者信息

Tedesco Pietro, Fisichella Piero M, Way Lawrence W, Patti Marco G

机构信息

Department of Surgery, University of California San Francisco, San Francisco, CA, USA.

出版信息

Am J Surg. 2005 Dec;190(6):891-4. doi: 10.1016/j.amjsurg.2005.08.016.

Abstract

BACKGROUND

Epiphrenic diverticula of the esophagus are often associated with a concomitant esophageal motor disorder, which is thought to be the cause of the diverticulum and some of the patient's symptoms. At one time diverticula were best removed via a left thoracotomy, but now the operation can be performed laparoscopically in most cases. We hypothesized that: (1) a motor disorder is the underlying cause of the diverticulum; and (2) optimal treatment consists of laparoscopic resection of the diverticulum, a Heller myotomy, and Dor fundoplication.

METHODS

We performed a retrospective review of a prospectively collected database from a university hospital tertiary care center. Between June 1994 and December 2002, we evaluated 21 patients with epiphrenic diverticula. An associated motility disorder of the esophagus was found in 81% of patients (achalasia, 9%; diffuse esophageal spasm, 24%; nonspecific esophageal motility disorder, 24%; nutcracker esophagus, 24%). Seven (33%) of these patients, all with esophageal dysmotility, were referred for treatment. The laparoscopic operation entailed resection of the diverticulum (using an endoscopic stapler), a Heller myotomy, and a Dor fundoplication.

RESULTS

All operations were completed laparoscopically. The postoperative course of 6 patients was uneventful and they left the hospital after 72 +/- 21 hours. In 1 patient an acute paraesophageal hernia developed, which was repaired on the second postoperative day. Late follow-up (median 57 months) showed that all 7 patients were asymptomatic.

CONCLUSIONS

These data support the conclusions that: (1) a primary esophageal motility disorder is the underlying cause of most epiphrenic diverticula; and (2) laparoscopic treatment is successful and should be the method of choice. The diverticular neck can be exposed satisfactorily from the abdomen; a stapler inserted from this angle is better orientated to transect the neck than one inserted through a thoracoscopic approach. Furthermore, the myotomy and fundoplication are much more easily performed from the abdomen than from alternative approaches.

摘要

背景

食管膈上憩室常伴有食管运动障碍,后者被认为是憩室形成及部分患者症状的病因。过去,憩室最好通过左胸切开术切除,但现在大多数情况下可通过腹腔镜进行手术。我们推测:(1)运动障碍是憩室的根本病因;(2)最佳治疗方法是腹腔镜下切除憩室、行Heller肌切开术及Dor胃底折叠术。

方法

我们对一所大学医院三级护理中心前瞻性收集的数据库进行了回顾性分析。1994年6月至2002年12月期间,我们评估了21例食管膈上憩室患者。81%的患者存在相关的食管动力障碍(贲门失弛缓症9%;弥漫性食管痉挛24%;非特异性食管动力障碍24%;胡桃夹食管24%)。其中7例(33%)患者均有食管动力障碍,被转诊接受治疗。腹腔镜手术包括切除憩室(使用内镜吻合器)、Heller肌切开术及Dor胃底折叠术。

结果

所有手术均通过腹腔镜完成。6例患者术后恢复顺利,术后72±21小时出院。1例患者术后出现急性食管旁疝,于术后第二天进行了修补。远期随访(中位时间57个月)显示,所有7例患者均无症状。

结论

这些数据支持以下结论:(1)原发性食管动力障碍是大多数食管膈上憩室的根本病因;(2)腹腔镜治疗成功,应作为首选方法。从腹部可满意暴露憩室颈部;从这个角度插入吻合器比通过胸腔镜途径插入更有利于横断颈部。此外,与其他途径相比,从腹部进行肌切开术和胃底折叠术更容易。

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