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急性中毒的临床与药学方面

Clinical and pharmaceutical aspects in acute poisoning.

作者信息

Van Kesteren R G, Uges D R

机构信息

Department of Reanimation and Clinical Toxicology, University Hospital Utrecht, The Netherlands.

出版信息

Pharm Weekbl Sci. 1992 Jun 19;14(3):78-82. doi: 10.1007/BF01962690.

DOI:10.1007/BF01962690
PMID:1630875
Abstract

Today there are several methods for treating intoxicated patients. If these patients arrive in hospital in time, the diagnosis is correct and appropriate therapy is instituted, nearly all survive without any physical damage. This is best achieved by team-work between the hospital pharmacist and the physician treating the patient. Both should have a sound knowledge of the toxicological properties of drugs and other poisons and the clinical features which they produce. This article emphasizes the need for close co-operation between the pharmacist and the physician and discusses specific therapeutic measures, such as prevention of absorption, acceleration of elimination, symptomatic therapy and administration of antagonists.

摘要

如今,有多种方法可用于治疗中毒患者。如果这些患者及时抵达医院,诊断正确且采取了适当的治疗措施,几乎所有患者都能存活且无任何身体损伤。这最好通过医院药剂师和治疗患者的医生之间的团队合作来实现。双方都应具备扎实的药物和其他毒物毒理学特性以及它们所产生的临床特征方面的知识。本文强调了药剂师和医生密切合作的必要性,并讨论了具体的治疗措施,如防止吸收、加速排泄、对症治疗和使用拮抗剂。

相似文献

1
Clinical and pharmaceutical aspects in acute poisoning.急性中毒的临床与药学方面
Pharm Weekbl Sci. 1992 Jun 19;14(3):78-82. doi: 10.1007/BF01962690.
2
[Active involvement of pharmacists in initial treatments for acute poisoning and overdosed patients in the intensive care unit].[药剂师积极参与重症监护病房急性中毒和用药过量患者的初始治疗]
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[Role of the pharmacist in treatment for specific poisons and drugs].[药剂师在特定毒物和药物治疗中的作用]
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[Role and duties performed by a toxicologic laboratory in diagnosis of acute poisoning].[毒理学实验室在急性中毒诊断中的作用及履行的职责]
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Transport management of the patient with acute poisoning.
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[Guidelines for the treatment of acute chemical poisoning--10--symptomatic therapy. The measures against convulsions].急性化学中毒治疗指南——10——对症治疗。抗惊厥措施
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本文引用的文献

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Enhancement of theophylline clearance by oral activated charcoal.口服活性炭对茶碱清除率的提高作用。
Clin Pharmacol Ther. 1983 Mar;33(3):351-4. doi: 10.1038/clpt.1983.44.
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Physostigmine salicylate in the treatment of tricyclic antidepressant overdosage.水杨酸毒扁豆碱治疗三环类抗抑郁药过量
JAMA. 1975 Mar 3;231(9):941-3.
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[Orphenadrine poisoning (Disipal)].奥芬那君中毒(地西泮)
Ned Tijdschr Geneeskd. 1978 Jul 8;122(27):988-92.