Furberg H, Bulik C M, Lerman C, Lichtenstein P, Pedersen N L, Sullivan P F
Department of Genetics, University of North Carolina, Chapel Hill, NC 27599-7264, USA.
Tob Control. 2005 Dec;14(6):422-4. doi: 10.1136/tc.2005.012476.
Nicotine replacement therapies (NRT) are an effective treatment for tobacco dependence, yet most smokers do not quit or remain abstinent. We investigated whether Swedish snus (snuff) use was associated with smoking cessation among males participating in a large population based twin study in Sweden. Snus use was associated with smoking cessation but not initiation. Given that snus delivers comparable nicotine concentrations but carries lesser cancer risk than cigarettes, snus may be a widely used, non-medical form of NRT. Evaluation of the efficacy of snus for smoking cessation should be evaluated in randomised clinical trials.
尼古丁替代疗法(NRT)是治疗烟草依赖的有效方法,但大多数吸烟者并未戒烟或保持戒烟状态。我们调查了在瑞典一项基于大规模人群的双胞胎研究中,男性使用瑞典鼻烟与戒烟之间是否存在关联。使用鼻烟与戒烟有关,但与开始吸烟无关。鉴于鼻烟提供的尼古丁浓度相当,但比香烟带来的癌症风险更小,鼻烟可能是一种广泛使用的非医学形式的尼古丁替代疗法。应在随机临床试验中评估鼻烟戒烟的疗效。