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[区域淋巴结反应及喉癌肿瘤淋巴-细胞浸润的预后意义]

[Prognostic significance of the reaction of regional lymph nodes and lymphoid-cellular infiltration of the tumor in laryngeal cancer].

作者信息

Ol'khovskaia I G, Matiakin E G

出版信息

Vestn Otorinolaringol. 1992 Mar-Apr(2):12-4.

PMID:1632026
Abstract

The immune response of the primary tumor and regional lymph nodes was studied morphologically in 239 patients with vestibular cancer of the larynx. Marked infiltration of the stroma developed in 48, mild response or its absence were recorded in 97 patients. The difference in 5-year survival was significant (84 versus 62%). Out of 117 patients examined for B-dependent cortical and T-dependent paracortical response of the lymph nodes, 5-year survival in hyperplasia of the zones appeared to be 67%, in the absence of hyperplasia 42% and 44%, respectively. The difference is significant. The responses were essential for prognostication of the patient' survival.

摘要

对239例喉前庭癌患者的原发肿瘤和区域淋巴结的免疫反应进行了形态学研究。48例出现明显的间质浸润,97例记录为轻度反应或无反应。5年生存率的差异具有显著性(分别为84%和62%)。在对117例患者的淋巴结进行B细胞依赖的皮质区和T细胞依赖的副皮质区反应检查中,区域增生患者的5年生存率为67%,无增生患者的5年生存率分别为42%和44%。差异具有显著性。这些反应对患者生存的预后至关重要。

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