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中重度贫血患者的缺铁性贫血

Iron deficiency anaemia in moderate to severely anaemic patients.

作者信息

Idris Muhammad

机构信息

Department of Pathology, Ayub Medical College, Abbottabad.

出版信息

J Ayub Med Coll Abbottabad. 2005 Jul-Sep;17(3):45-7.

Abstract

BACKGROUND

Anaemia is defined as a clinical abnormality characterized by reduction in haemoglobin concentration below the normal for age, sex, physiological condition and altitude from the sea level of a person. It can be of different types, the commonest being iron deficiency anaemia which affects mostly pregnant and lactating females and growing children in the developing world. The present study was conducted at Ayub Teaching Hospital on this problem of global importance.

METHODS

One hundred consecutive anaemic patients were selected from Ayub Teaching Hospital. After detailed history and examination, preliminary blood tests including full blood counts, platelets count, retics count, absolute blood values and blood film examination (all tests done by visual method) were done in the laboratories of Ayub Teaching Hospital and Ayub Medical College, Abbottabad. A clinical diagnosis was made based upon the findings of history, examination and blood tests. In patients suspected to have iron deficiency anaemia, serum iron studies (i.e. serum iron, Total iron binding capacity (TIBC) and serum ferritin) were done to confirm the diagnosis.

RESULTS

Sixty eight patients were found to have iron deficiency anaemia. Females were affected more than the males. Female to male ratio being 1:5:1. Majority of the patients (82.2%) were aged 21-60 years. However, there were two peaks (21% & 25%) in age groups 21-30 and 41-50 respectively. Based upon serum ferritin concentrations, most of the patients were found to suffer from moderate iron deficiency anaemia (53%).

CONCLUSION

Iron deficiency anaemia is the commonest type of anaemia in our area. It is more common in females. It is more common in age group 21-60 years, with two peaks, one in 21-30 years and the other in 41-50 years.

摘要

背景

贫血被定义为一种临床异常,其特征是血红蛋白浓度低于根据一个人的年龄、性别、生理状况以及相对于海平面的海拔高度所确定的正常水平。贫血有不同类型,最常见的是缺铁性贫血,在发展中国家,这种贫血主要影响孕妇、哺乳期女性以及成长中的儿童。本研究在阿尤布教学医院针对这一具有全球重要性的问题展开。

方法

从阿尤布教学医院连续选取了100名贫血患者。在进行详细的病史询问和检查后,在阿尤布教学医院和阿伯塔巴德的阿尤布医学院实验室进行了初步血液检查,包括全血细胞计数、血小板计数、网织红细胞计数、绝对血细胞值以及血涂片检查(所有检查均采用目视法)。根据病史、检查和血液检查结果做出临床诊断。对于疑似缺铁性贫血的患者,进行血清铁研究(即血清铁、总铁结合力(TIBC)和血清铁蛋白)以确诊。

结果

发现68名患者患有缺铁性贫血。女性受影响的人数多于男性,男女比例为1.5:1。大多数患者(82.2%)年龄在21至60岁之间。然而,在21至30岁和41至50岁年龄组分别有两个峰值(21%和25%)。根据血清铁蛋白浓度,大多数患者被发现患有中度缺铁性贫血(53%)。

结论

缺铁性贫血是我们地区最常见的贫血类型。在女性中更为常见。在21至60岁年龄组更为常见,有两个峰值,一个在21至30岁,另一个在41至50岁。

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