Zhou Bin, Gao Wen-yuan, Zhang Tie-jun, Chen Hai-xia
School of Pharmaceutical Science and Technology, Tianjin University, Tianjin 300072, China.
Zhongguo Zhong Yao Za Zhi. 2005 Sep;30(17):1313-6.
This paper reviewed application of chitin and its derivatives in pharmaceutical industry of traditional Chinese medicine in recent years. Chitin and its derivatives could be used as a clarificant, retaining active substances, stabiliting preparation, reducing the heavy metals of traditional Chinese medicine extraction. Because of their churacteristics in biodegradation, biocompatibility and its tendency to film easily, chitin and its derivatives was ideal assistant materials in traditional Chinese medicine. Its application was largely enhanced after chitosan was modified. The problems and prospects of the application of chitin and its derivatives were also discussed.
本文综述了近年来甲壳素及其衍生物在中药制药行业中的应用。甲壳素及其衍生物可用作澄清剂，保留活性成分，稳定制剂，降低中药提取物中的重金属含量。由于其具有生物降解性、生物相容性以及易于成膜的特性，甲壳素及其衍生物是中药理想的辅助材料。壳聚糖改性后其应用得到了很大的拓展。文中还讨论了甲壳素及其衍生物应用中存在的问题及前景。
