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猿猴病毒40诱导的仓鼠淋巴瘤的B细胞起源

B-cell origin of hamster lymphoid tumors induced by simian virus 40.

作者信息

Coe J E, Green I

出版信息

J Natl Cancer Inst. 1975 Jan;54(1):269-70. doi: 10.1093/jnci/54.1.269.

DOI:10.1093/jnci/54.1.269
PMID:163322
Abstract

Two lymphoid neoplasms induced by simian virus 40 (SV40) in Syrian hamsters were analyzed for lymphocyte characteristics. The hymphocytes from both tumors contained membrane-bound Ig that was exclusively of 7Sgamma2 class. Furthermore, neither lymphoid tumor had a complement receptor. Thus both tumors oringinated from a particular B-cell population, which suggests that this B-cell type is associated with an SV40 receptor.

摘要

对由猿猴病毒40(SV40)诱导叙利亚仓鼠产生的两种淋巴样肿瘤进行了淋巴细胞特征分析。两种肿瘤的淋巴细胞均含有膜结合免疫球蛋白,且均为7Sγ2类。此外,两种淋巴样肿瘤均无补体受体。因此,这两种肿瘤均起源于特定的B细胞群体,这表明这种B细胞类型与SV40受体有关。

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