Phillips J T, Duncan W R, Streilein J W
Immunogenetics. 1981 Mar 1;12(5-6):485-96. doi: 10.1007/BF01561690.
Immunochemical comparisons between hamster cell-surface p39/p29 alloantigens and putative MHC class I and II products indicate that p39/p29 alloantigens are probable class II products. Both p39/p29 alloantigens and class II homologues have varying expression in hamster lymphoid tissues and are absent from fibroblasts. In addition, analysis by nonequilibrium pH gradient electrophoresis demonstrates similar, although nonidentical, alloantigen and class II homologous charge profiles. This observation could reflect multiple class II subregions within the hamster MHC. These data therefore suggest an immunochemical description of the hamster MHC which is compatible with MHC models proposed for other mammalian species.
仓鼠细胞表面p39/p29同种异体抗原与假定的MHC I类和II类产物之间的免疫化学比较表明，p39/p29同种异体抗原可能是II类产物。p39/p29同种异体抗原和II类同源物在仓鼠淋巴组织中具有不同的表达，而成纤维细胞中则不存在。此外，非平衡pH梯度电泳分析表明，同种异体抗原和II类同源物的电荷分布相似但不完全相同。这一观察结果可能反映了仓鼠MHC内的多个II类亚区。因此，这些数据提示了一种与其他哺乳动物物种所提出的MHC模型相一致的仓鼠MHC免疫化学描述。
