Younis Azza I H, Bassiouny Safiya, Abdel Aziz Jomana, Khalafallah Osama
Department of Parasitology, Faculty of Medicine, Cairo University, Egypt.
J Egypt Soc Parasitol. 2005 Dec;35(3):1019-26.
The estimation of the serum adhesion molecules (ICAM-2) levels in experimental trichinosis and evaluation of its impact on the course of infection as well as its possible role in the diagnosis of early trichinosis were studied. Serum levels of ICAM-2 correlated significantly with the inflammatory and course sequences of trichinosis in mice and had a similar relation with blood eosinophilia. So, estimation of ICAM-2 serum levels may prove useful in diagnosis of trichinosis recent infections, and in monitoring the prognosis and response to treatment. Investigations of the ICAM-2 role in human trichinosis and applying the findings to improve the diagnostic approaches are highly recommended.
研究了实验性旋毛虫病中血清黏附分子（ICAM - 2）水平的评估，及其对感染进程的影响以及在早期旋毛虫病诊断中的可能作用。ICAM - 2的血清水平与小鼠旋毛虫病的炎症和病程显著相关，与血液嗜酸性粒细胞增多也有类似关系。因此，估计ICAM - 2血清水平可能有助于诊断近期的旋毛虫感染，以及监测预后和治疗反应。强烈建议研究ICAM - 2在人类旋毛虫病中的作用，并将研究结果应用于改进诊断方法。
